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Oulu, Finland Clinical Trials

A listing of Oulu, Finland clinical trials actively recruiting patients volunteers.

RESULTS

Found (76) clinical trials

Safety of Spinal Anesthesia in Patients With Tibial Shaft Fracture

For some of the patients RA may be even more safe than GA. According to a large meta-analysis RA reduces the risk of several complications versus GA. Risk of deep vein thrombosis is reduced by 44% Risk of pulmonary embolism is reduced by 55 % Risk of major bleeding is ...

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Synthetic vs Natural Estrogen in Combined Oral Contraception

The main objective of the study is to compare the metabolic effects of natural estradiol and synthetic ethinylestradiol used in combined oral contraception in healthy women. A progestin-only preparation will be used in comparison. The main goal is to study the effects on glucose metabolism, coagulation and a markers of ...

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Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology Triggers and Outcome

BACKGROUND: In industrialized countries a considerable and increasing proportion of strokes occur at younger ages. Stroke at young age causes marked disability at worst and thus long-standing socioeconomic consequences and exposes survivors for 4-fold risk of premature death compared with background population. Up to 50% of young patients with ischemic ...

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Type 1 Diabetes Prediction and Prevention (DIPP) Study

Briefly, cord blood samples are collected and HLA-DR-DQ genotypes are determined from newborn babies. Families with a newborn baby carrying a DR-DQ genotype associated with increased risk for T1D are invited to participate in regular follow-up at the age of 3, 6, 9, 12, 18 and 24 months, and thereafter ...

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Collagen Implant Compared to Gluteus Maximus Flap for Reconstruction of Pelvic Floor After ELAPE/EAPE in Rectal Cancer

Extended abdominoperineal excision (EAPE) of the rectum is the potentially curative operation for rectal carcinomas too low for primary anastomosis, especially if the levator and sphincter musculature is infiltrated. This enlarged operation, when the levator musculature is excised en bloc with the rectum, creates a large defect. Primary closure is ...

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A Study of Surgical Weight Loss to Treat Obstructive Sleep Apnea

Sleep disturbances have become a public health concern in the modern society, affecting millions of people. Obstructive sleep apnea (OSA) is one of the commonest sleep disturbances. Obstructive sleep apnea affects mostly middle-aged work force, causing a negative impact on public health since it increases both mortality and morbidity. In ...

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Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

This study evaluates the effect of different induction courses in children and adolescents with newly diagnosed acute myeloid leukemia. In the first course patients are randomised to receive either standard anthracycline therapy with mitoxantrone or experimental DaunoXome. In the second course patients are randomised between standard treatment with ADxE (cytarabine, ...

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Comparison of Titanium-Nitride-Oxide Coated Bio-Active-Stent (Optimax ) to the Drug (Everolimus) -Eluting Stent (Synergy ) in Acute Coronary Syndrome

Coronary artery disease (CAD) is the most frequent cause of death, accounting for approximately 13% of all deaths. In western countries, the incidence of ST-segment elevation myocardial infarction (STEMI) is around 77/100 000/year, whereas in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), the incidence is 132/100 000/year. Thus, the ...

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Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

The REFINE ICD trial will assess whether prophylactic ICD therapy, guided by non-invasive risk assessment tools, reduces mortality in MI survivors with better-preserved LV function.

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Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome

The study population consists of women of reproductive age with PCOS, no wish of pregnancy and no other contraindications to hormonal contraceptives. The volunteer subjects will be recruited from hospital's patient files with PCOS (IC diagnosis E.28.2). Methods Sample size Our previous study comparing the metabolic effects of the same ...

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