Copehagen South, Denmark Clinical Trials

A listing of Copehagen South, Denmark clinical trials actively recruiting patients volunteers.

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Found 67 clinical trials
Bioflow-DAPT Study

BIOFLOW-DAPT is a prospective, multi-center, international, two-arm randomized controlled clinical study. A total of 1'948 subjects will be randomized 1:1 to receive either Orsiro or Resolute Onyx. After index procedure, all patients will receive DAPT (ASA + P2Y12 inhibitor) for 30 days, followed by monotherapy with either P2Y12 inhibitor or …

cancer
dapt
aspirin
stroke
percutaneous coronary intervention
Herlev og Gentofte Hospital
 (3.9 away) Contact site
  • 50 views
  • 14 May, 2021
  • +27 other locations
Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.

This study evaluates the benefits and harms of goal directed fluid removal with furosemide versus placebo in critical ill adult patients with fluid overload in the intensive care unit. Half of the patients will receive furosemide and the other half placebo. The treatment will continue until the excess fluid is …

norepinephrine
edema
furosemide
Department of Intensive Care, Rigshospitalet
 (2.2 away) Contact site
  • 0 views
  • 09 Jul, 2021
  • +11 other locations
Handling Oxygenation Targets in COVID-19

Patients with COVID-19 and hypoxaemic respiratory failure and admitted to the intensive care unit (ICU) are treated with supplementary oxygen as a standard. However, quality of quantity evidence regarding this practise is low. The aim of the HOT-COVID trial is to evaluate the benefits and harms of two targets of …

Dept. of Intensive Care, Herlev Hospital
 (7.1 away) Contact site
  • 5 views
  • 25 Jan, 2021
  • +7 other locations
The Effect of Dupilumab on Lung Function and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma

Primary Objective: To assess the effect of dupilumab on lung function and related changes in airway volumes detectable by functional respiratory imaging Secondary Objective: To evaluate the effect of dupilumab at Week 24 on bronchodynamics, hyperinflation, airway resistance, airway wall thickness, ventilation defects and mucus plugging derived from high-resolution computed …

fractional exhaled nitric oxide
bronchodilator
pulmonary function test
leukotriene receptor antagonist
spirometry
Investigational Site Number 2080002
 (2.2 away) Contact site
  • 12 views
  • 22 Jul, 2021
  • +62 other locations
Effect of Combinations of Paracetamol Ibuprofen and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty

Multimodal pain management is essential for recovery after surgery, aiming to target different pain mechanisms to minimize opioid usage and opioid-related adverse effects. Evidence for benefits and harms of various non-opioid analgesic combinations is, however, nearly non-existing, and large-scale trials are urgently needed. Recently, the investigators have demonstrated that combining …

analgesics
analgesia
hip arthroplasty
ibuprofen
opioid
Bispebjerg Hospital
 (3.1 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • +8 other locations
Targeted Potassium Levels for Prevention of ICD Therapy

This study evaluates whether a rigorously controlled high-normal level of serum-potassium (4.5-5.0 mEq/L) using dietary recommendations, potassium supplements and mineralocorticoid receptor antagonists will results in a lower incidence of cardiac arrhythmias in patients with an ICD. Patients will be randomized to this treatment or a control arm, where patients will …

implantable cardioverter-defibrillators
cardiac resynchronization therapy
potassium
arrhythmia
Gentofte University Hospital
 (3.9 away) Contact site
  • 30 views
  • 24 Jan, 2021
  • +1 other locations
DANHEART (H-HeFT and Met-HeFT)

The present study is testing in a combined design to types of drugs in patients with chronic heart failure: 1) Hydralazine in combination with isosorbide dinitrate (BiDil) and 2) Metformin hydrochloride. The study is double blind, placebo controlled. The first hypothesis is that hydralazine in combination with isosorbide dinitrate can …

aldosterone
systolic blood pressure
hemoglobin a1c
hydralazine
type 2 diabetes mellitus
Sj llands Universitetshospital, Roskilde
 (18.8 away) Contact site
  • 62 views
  • 18 Mar, 2021
  • +32 other locations
The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial

The purpose of this trial is to assess patient important benefits and harms of IV fluid restriction vs. standard care fluid therapy in patients with septic shock.

crystalloid solutions
sepsis
lactic acid
fluid therapy
vasoconstrictor
Dept of Intensive Care,Copenhagen University Hospital Rigshospitalet
 (2.2 away) Contact site
  • 8 views
  • 29 Jan, 2021
  • +48 other locations
Botox on Vulvar Vestibulitis

The study seeks to evaluate the effect of botulinum toxin on vulvar vestibulitis (VVS) after local injection with Botox, a potential treatment to relieve patients of vulvar pain, reducing the need for painkillers, and improving the sexual quality of life of the patients.

botulinum toxin
local injection
botox
analgesic
vulvodynia
Rigshospitalet
 (2.2 away) Contact site
  • 4 views
  • 07 Nov, 2020
  • 1 location
Study of Long-Term Use of Proton-Pump-Inhibitors in General Practice

The primary purpose of the study is to determine the effect of esomeprazole compared to placebo in patients from general practice who have previously been treated with proton-pump-inhibitors (PPI) and who have no upper endoscopic findings.

Department of gastroenterology, Glostrup University Hospital
 (6.1 away) Contact site
  • 1 views
  • 07 Nov, 2020
  • 1 location