Prague 10, Czech Republic Clinical Trials

A listing of Prague 10, Czech Republic clinical trials actively recruiting patients volunteers.

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Found 20 clinical trials
Trial of Andexanet in ICH Patients Receiving an Oral FXa Inhibitor

Randomized, controlled clinical trial evaluating the efficacy and safety of andexanet versus usual standard of care in patients with intracranial hemorrhage anticoagulated with a direct oral anticoagulant

VN
 (1.2 away) Contact site
  • 19 views
  • 17 Jul, 2021
  • +180 other locations
Investigation of Radium-223 Dichloride (Xofigo) a Treatment That Gives Off Radiation That Helps Kill Cancer Cells Compared to a Treatment That Inactivates Hormones (New Antihormonal Therapy NAH) in Patients With Prostate Cancer That Has Spread to the Bone Getting Worse on or After Earlier NAH

Researchers in this study want to compare how well drug radium-223 dichloride (Xofigo) and new (novel) anti-hormonal (NAH) therapy work in participants with prostate gland cancer which has spread to the bone and progressed on or after one line of NAH therapy. Meanwhile researchers want to compare the safety of …

Urocentrum Praha, s.r.o.
 (1.2 away) Contact site
  • 0 views
  • 16 Jul, 2021
  • +144 other locations
Right Ventricular Apical Versus True Mid-septal Pacing

Background Right ventricular (RV) artificial apical pacing can negatively impact synchrony of left ventricular contraction. The pacing from the septum of the RV can present an advantage in terms of less expressed dyssynchrony and reduced negative impact on left ventricular (LV) function. However, results of randomized studies comparing apical and …

Charles University in Prague
 (1.2 away) Contact site
  • 0 views
  • 22 Jun, 2021
  • 1 location
Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients

Cardiac allograft vasculopathy (CAV) represents the leading cause of late morbidity and mortality in heart transplant recipients as the second most frequent cause of all deaths at 3 years. In distinction from general coronary atherosclerosis, CAV affects diffusely the entire coronary vasculature with marked intimal proliferation and concentric vascular thickening …

Institute for Clinical and Experimental Medicine
 (1.2 away) Contact site
  • 1 views
  • 21 Feb, 2021
  • +2 other locations
INSULIN THERAPY DE-INTENSIFICATION WITH iGlarLixi

Intensive insulin therapy using multiple daily injections (MDI) constitutes the most intense type of regimen in type 2 diabetes mellitus (T2D). Although highly effective in lowering blood glucose, it can also increase the risk of hypoglycemia, promote weight gain and cause significant treatment burden for the patients. As demonstrated by …

Institute for Clinical and Experimental Medicine
 (1.2 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • 1 location
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

This study aims to determine if treatment with apixaban, compared with aspirin, will reduce the risk of ischemic stroke and systemic embolism in patients with device-detected sub-clinical atrial fibrillation and additional risk factors for stroke.

fibrillation
vascular disease
hypertension
stroke
atrial flutter
IKEM Institute for Clinical and Experimental Medicine
 (1.2 away) Contact site
  • 337 views
  • 26 Jan, 2021
  • +131 other locations
A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder

The primary objective is to evaluate the efficacy of monthly 225 mg sc fremanezumab in adult patients with migraine and major depressive disorder (MDD) The secondary objectives are to evaluate the efficacy of monthly 225 mg sc of fremanezumab in adult patients with migraine and MDD on the reduction of …

fremanezumab
depression
body mass index
major depressive disorder
headache
Teva Investigational Site 54185
 (1.8 away) Contact site
  • 360 views
  • 27 Apr, 2021
  • +64 other locations
A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Study 20170703 is a phase 4, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of erenumab against placebo in subjects with chronic migraine (CM) who have a history of at least 1 preventive treatment failure and are diagnosed with medication overuse headache (MOH).

acute headache
preventive medication
common migraine
erenumab
experimental drug
Thomayerova nemocnice
 (1.0 away) Contact site
  • 359 views
  • 02 Aug, 2021
  • +168 other locations
Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression

The purpose of this study is to compare the efficacy of vortioxetine versus desvenlafaxine after 8 weeks of treatment in patients that have tried one available treatment without getting the full benefit

selective serotonin reuptake inhibitors
antidepressants
paroxetine
depression
citalopram
Clintrial s.r.o. (CZ1001)
 (1.2 away) Contact site
  • 0 views
  • 28 Jun, 2021
  • +85 other locations
Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to Ustekinumab

The trial investigates the efficacy and safety of brodalumab against guselkumab in treatment for patients with moderate-to-severe plaque psoriasis who still have some remaining symptoms after ustekinumab treatment.

guselkumab
ustekinumab
plaque psoriasis
Pharma Investigational Site
 (1.2 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +70 other locations