Prague 10, Czech Republic Clinical Trials

A listing of Prague 10, Czech Republic clinical trials actively recruiting patients volunteers.

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Found 65 clinical trials
Pivotal Randomized Open-label Study of Optune (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

To test the effectiveness and safety of Optune given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune and maintenance temozolomide are continued following radiation therapy.

tumor treating fields therapy
tumor progression
karnofsky performance status
gross total resection
Na Homolce Hospital
 (1.2 away) Contact site
  • 26 Jul, 2021
  • +150 other locations
Early Detection of High Grade Ovarian Cancer Using Uterine Lavage EHUD Study and Duplex Sequencing

In Phase I the sponsor will systematically test conditions for lavage filtration that increase tumor cell fraction without reducing tumor mutation yield. The Sponsor will also transition all lavages to luteal phase timing, when endometrial shedding is least. In Phase II the Sponsor will examine our data in context of …

Charles University Prag
 (1.2 away) Contact site
  • 07 Apr, 2021
  • +8 other locations
AtaCor Subcostal Temporary Extravascular Pacing III Study

Third in-human study for the AtaCor Extravascular (EV) Temporary Pacing Lead System to collect initial safety and performance data for the latest AtaCor System. The objective of the study is to generate safety and performance data of the latest AtaCor EV Temporary Pacing Lead System 1) to support the development …

Na Homolce Hospital
 (1.2 away) Contact site
  • 22 Jun, 2021
  • +4 other locations
The ARIES HeartMate 3 Pump IDE Study

Prospective, randomized, double-blinded, placebo-controlled clinical investigation of advanced heart failure patients treated with the HM3 with two different antithrombotic regimens: vitamin K antagonist with aspirin versus vitamin K antagonist with placebo

heart failure
IKEM Prague
 (1.2 away) Contact site
  • 16 May, 2021
  • +30 other locations
ABILITY Diabetes Global

To compare in diabetic patients eligible for percutaneous coronary intervention (PCI) with minimal exclusion criteria, the efficacy and safety of Abluminus DES+ sirolimus- eluting stents (SES) versus XIENCE Everolimus-Eluting Stents (EES). At least 40% of patients are expected to be affected by multivessel coronary artery disease and 30% with acute …

stable angina
diabetes mellitus
arterial disease
University Hospital Kr lovsk Vinohrady, Department of Medecine Cardiology
 (1.2 away) Contact site
  • 25 Jan, 2021
  • +85 other locations
sFlt1/PlGF and Selective Labor Induction to Prevent Preeclampsia at Term

Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world. Term PE accounts for 70% of all PE and a large proportion of maternal-fetal morbidity related with this condition. Prediction and …

Institute for the Care of Mother and Child
 (1.2 away) Contact site
  • 15 May, 2021
  • +13 other locations
FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

This clinical investigation is intended to demonstrate the safety and effectiveness of ventricular ablation therapy using the FlexAbility Sensor Enabled Ablation Catheter in patients with drug-refractory monomorphic ventricular tachycardia in whom ventricular tachycardia recurs despite antiarrhythmic drug therapy or when antiarrhythmic drugs are not tolerated or desired.

ejection fraction
catheter ablation
Nemocnice Na Homolce
 (1.2 away) Contact site
  • 25 Jan, 2021
  • +29 other locations
A Multicentre European Study to Evaluate Granulox Used in the Treatment Pathway of Predominantly Chronic Venous Leg Ulcers (VLUs).

The investigation is designed as an open label, randomized, prospective, assessor blinded, multi centre investigation. 254 evaluable subjects will be randomized to either standard of care group or standard of care with Granulox added as an adjunct therapy in predominantly venous leg ulcer subjects. Standard of care wound management will …

compression therapy
immunosuppressive agents
systemic steroids
venous insufficiency
foot ulcer
U Nemocnice v Praze
 (1.2 away) Contact site
  • 08 May, 2021
  • +36 other locations
Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation

Electrical source imaging is part of the presurgical evaluation of patients with drug-resistant focal epilepsy. The software packages that will be used in this study have Declaration of Conformity within the European Economic Area (CE mark) for this specific medical use. In spite of being part of the clinical standard, …

epilepsy surgery
epilepsy monitoring
Motol University Hospital
 (1.2 away) Contact site
  • 03 Feb, 2021
  • +12 other locations
TactiFlex AF IDE Trial

Prospective, non-randomized multi-center clinical investigation. Design includes a main study and a separate substudy. Subjects in the main study are to be treated using the full range of ablation power settings in the IFU. Subjects in the substudy are to be treated in the upper end of the recommended ablation …

af 3
radiofrequency ablation
catheter ablation
antiarrhythmic drug
IKEM Prague
 (1.2 away) Contact site
  • 05 Jun, 2021
  • +43 other locations