Bogota, Colombia Clinical Trials

A listing of Bogota, Colombia clinical trials actively recruiting patients volunteers.

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Found 59 clinical trials
Efficacy Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy Compared With Placebo in Adult Patients With NASH and Liver Fibrosis.

Randomized, double-blind, parallel-group, multicenter study to assess efficacy, safety, and tolerability of oral tropifexor & licogliflozin combination therapy and each monotherapy, compared with placebo for treatment of adult patients with nonalcoholic steatohepatitis (NASH) and liver fibrosis

  • 27 views
  • 26 Jul, 2021
  • 96 locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

right heart catheterization
connective tissue disease
left ventricular end-diastolic pressure
macitentan
septal defect
  • 56 views
  • 16 Jul, 2021
  • 266 locations
A Safety Study of Pimavanserin in Adult and Elderly Subjects Experiencing Neuropsychiatric Symptoms Related to Neurodegenerative Disease

The purpose of this study is to assess the safety and tolerability of pimavanserin compared to placebo in adult and elderly subjects with neuropsychiatric symptoms related to neurodegenerative disease.

  • 116 views
  • 09 Jul, 2021
  • 125 locations
An Innovative Treatment for Cervical Precancer (UH3)

The purpose of this academic-industrial partnership will compare the CryoPen and thermoablator to traditional CO2-based cryotherapy for the treatment of cervical precancer in low and middle income countries (LMICs) and investigate whether the cure rates of cervical intraepithelial neoplasia 2 and more severe diagnoses (CIN2+) with these devices are non-inferior …

cin 3
cervical dysplasia
cervical high grade squamous intraepithelial lesion
cervical intraepithelial neoplasia grade 2
cryotherapy
  • 43 views
  • 03 Feb, 2021
  • 4 locations
Dolutegravir and Darunavir Evaluation in Adults Failing Therapy

DEFT is a randomised, open-label study in HIV-1 infected patients failing first-line antiretroviral therapy (ART). The study compares 2 regimens of second-line ART (dolutegravir and darunavir pharmaco-enhanced with ritonavir and dolutegravir and 2 prespecified NRTIs) with the WHO recommended regimen of 2NRTIs plus a ritonavir-boosted PI (Standard of Care (SOC)). …

antiretroviral agents
reverse transcriptase inhibitor
antiretroviral therapy
darunavir
ritonavir
  • 1172 views
  • 25 Mar, 2021
  • 32 locations
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with Pulmonary Arterial Hypertension (PAH) in comparison to placebo.

right heart catheterization
endothelin receptor antagonist
heart disease
endothelin
pulmonary arterial hypertension
  • 169 views
  • 18 Jul, 2021
  • 150 locations
Efficacy and Safety of Erenumab in Pediatric Subjects With Episodic Migraine

This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with episodic migraine. The study hypothesis is that in pediatric subjects with episodic migraine, the combined erenumab dose group has a greater reduction from baseline …

episodic migraine
erenumab
headache
  • 226 views
  • 30 Jul, 2021
  • 179 locations
Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine

This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with chronic migraine. The study hypothesis is that in pediatric subjects with chronic migraine, the combined erenumab dose group has a greater reduction from baseline …

erenumab
headache
chronic migraine
  • 119 views
  • 30 Jul, 2021
  • 172 locations
Randomized Double-blind Efficacy and Safety Study of Doravirine/Islatravir (DOR/ISL) in Treatment-na ve Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-020)

This is a phase 3, randomized, controlled, double-blind, multisite clinical study of a once-daily fixed dose combination (FDC) of 100 mg doravirine/0.75 mg islatravir (DOR/ISL [also known as MK-8591A]) in treatment-nave participants with human immunodeficiency virus type-1 (HIV-1) infection. The primary objectives are to evaluate the antiretroviral activity, safety, and …

  • 4 views
  • 01 Aug, 2021
  • 93 locations
D9319C00001- 1L OC Mono Global RCT

This is a Phase III, randomised, double-blind, placebo-controlled, multicentre, international study assessing the efficacy and safety of maintenance olaparib compared with placebo in BRCAwt participants with Stage III to IV high grade serous or endometroid ovarian cancer (including fallopian tube cancer or primary peritoneal cancer) who are in complete or …

fallopian tube
tumor debulking
platinum-based chemotherapy
peritoneal cancer
olaparib
  • 0 views
  • 22 Jul, 2021
  • 82 locations