Shanghai City, China Clinical Trials

A listing of Shanghai City, China clinical trials actively recruiting patients volunteers.

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Found 100 clinical trials
A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer

The purpose of this study is to confirm the tolerability of recommended Phase 2 dose (RP2D) of Lazertinib (Phase 1), to determine the tolerability and identify the recommended Phase 2 combination dose of Lazertinib when combined with Amivantamab (Phase 1b), to characterize the safety and tolerability of Lazertinib and Amivantamab …

kinase inhibitor
growth factor
lung carcinoma
Shanghai Chest Hospital
 (3.0 away) Contact site
  • 15 Jun, 2021
  • +86 other locations
the Safety Tolerability Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets

Multiple Dose Safety, Tolerability, PK PD and Food Effect Study of HEC83518 in Healthy Subjects

The Shanghai Xuhui Central Hospital
 (0.0 away) Contact site
  • 16 May, 2021
  • 1 location
The Safety Tolerability and Pharmacokinetics of SYHX1901 Tablets in Chinese Healthy Subjects

This is a phase I clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of single ascending doses and multiple ascending doses of SYHX1901 tablets in Chinese healthy subjects

Huashan hospital of fudan university
 (1.7 away) Contact site
  • 10 Jun, 2021
  • 1 location
Induction Chemotherapy Combined With Toripalimab in Locoregionally-Advanced Laryngo-Hypopharyngeal Squamous Cell Cancer

This is a non-randomized phase 1, open-labeled clinical study, 1-arm, single center, to observe efficacy and safety of chemotherapy plus PD-L1 antibody Toripalimab every 21 days for 2 cycles as induction regimen in locoregionally-advanced laryngo-hypopharyngeal squamous cell cancer patients.

Department of Oncology, Ruijin Hospital
 (1.1 away) Contact site
  • 17 Jun, 2021
  • 1 location
Phase I Study of Iressa and CRT/IMRT in Chinese Patients With IIIB/IV NSCLC After Failure of Platinum-Based Chemotherapy

The primary objective of this study is to evaluate the tolerability and the maximum tolerated dose of Conformal or Intensity-Modulated Radiotherapy when given in combination with gefitinib 250mg in Chinese patients with IIIB or IV NSCLC after failure of platinum-based chemotherapy. Secondary objectives of the study are to obtain the …

platinum-based chemotherapy
pleural effusion
neutrophil count
cancer chemotherapy
Fudan University, Cancer Hospital, Department of Radiation Oncology
 (1.8 away) Contact site
  • 07 Nov, 2020
  • 1 location
Study of Apatinib as an Inhibitor of Tumor Angiogenesis

Apatinib is a tyrosin-inhibitor agent targeting at vascular endothelial growth factor receptor (VEGFR), so it can inhibit tumor angiogenesis. This phase I study aims to determine the drug's toxicity and to find a dose level to be used in a phase II study in solid tumor patients.

growth factor
neutrophil count
solid tumor
Fudan University Cancer Hospital
 (2.3 away) Contact site
  • 07 Nov, 2020
  • 1 location
A Randomised Trial of Cabazitaxel Docetaxel Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients Without Metastasis

Current agents administered in therapeutic regimens of prostate cancer employ different mechanisms to eliminate neoplastic cells by inducing substantial apoptosis and causing tumor regression. Treatment with neoadjuvant chemotherapy before radical prostatectomy may better control the tumor before it has the chance to convert into the disease of castration-resistant prostate cancer …

Zhongshan Hospital
 (2.3 away) Contact site
  • 26 Jan, 2021
  • +1 other locations
Phase I Study to Compare CMAB818 Injection and Lucentis in Patients With Wet AMD

This is a randomized, double-blind, two-group parallel, positive-controlled clinical Phase I trial comparing the safety, pharmacokinetics, pharmacodynamics and efficacy of CMAB818 and Lucentis in patients with wet age-related macular degeneration.

Shanghai General Hospital
 (1.9 away) Contact site
  • 18 Jun, 2021
  • +3 other locations
A Study of GMA301 in Subjects With Pulmonary Arterial Hypertension

A Randomized, Placebo-Controlled, Double-blind, Dose Escalation Study to Assess Safety, Efficacy and Pharmacokinetics of GMA301 Injection in Subjects with Pulmonary Arterial Hypertension

pulmonary arterial pressure
endothelin receptor antagonist
Shanghai Pulmonary Hospital
 (0.0 away) Contact site
  • 25 Jan, 2021
  • +7 other locations
The Safety Tolerability Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets in Chinses Healthy Subjects

The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets in Chinses Healthy Subjects

body mass index
The Shanghai xuhui district central hospital
 (0.0 away) Contact site
  • 16 May, 2021
  • 1 location