Shanghai City, China Clinical Trials

A listing of Shanghai City, China clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 25 clinical trials
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

testosterone
androgen suppression
MRI
prostate adenocarcinoma
androgen
Research Site
 (3.5 away) Contact site
  • 200 views
  • 23 Jul, 2021
  • +194 other locations
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

The purpose of the study is to determine if the combination of niraparib with Abiraterone Acetate (AA) plus prednisone compared with AA plus prednisone in participants with deleterious germline or somatic Homologous Recombination Repair (HRR) gene-mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC) provides superior efficacy in improving radiographic progression-free survival (rPFS).

Zhongshan Hospital,Fudan University
 (0.5 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +397 other locations
A Randomised Trial of Cabazitaxel Docetaxel Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients Without Metastasis

Current agents administered in therapeutic regimens of prostate cancer employ different mechanisms to eliminate neoplastic cells by inducing substantial apoptosis and causing tumor regression. Treatment with neoadjuvant chemotherapy before radical prostatectomy may better control the tumor before it has the chance to convert into the disease of castration-resistant prostate cancer …

Zhongshan Hospital
 (2.3 away) Contact site
  • 3 views
  • 26 Jan, 2021
  • +1 other locations
LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer

This is a single center, single arm Phase I study to establish the safety and efficacy of intravenously administered lentivirally transduced LIGHT-PSMA-specific CAR modified autologous T cells (PSMA-CART cells) in patients with CRPC.

metastasis
testosterone
abiraterone
tumor cells
serum testosterone
Changhai Hospital
 (5.5 away) Contact site
  • 2 views
  • 24 Jan, 2021
  • 1 location
A Study to Evaluate the Tolerance and Pharmacokinetics of TQB3720 Tablets

This study is conducted to investigate the pharmacokinetic and safety profiles of TQB3720 in patients with metastatic castration-resistant prostate cancer.

Fudan University Shanghai Cancer Center
 (2.3 away) Contact site
  • 0 views
  • 30 Apr, 2021
  • 1 location
A Study to Evaluate the Similarity in Pharmacokinetics and Safety of IBI310 and Ipilimumab YERVOY in Adult Healthy Chinese Male Volunteers

This trail will investigate the pharmacokinetics and safety of IBI310 and establish pharmacokinetics biosimilarity of IBI310 to ipilimumab YERVOY

Huashan Hospital Affiliated to Fudan University
 (1.7 away) Contact site
  • 0 views
  • 28 Jun, 2021
  • 1 location
Comparative Study of Abiraterone Acetate Tablets (I) or ZYTIGA in Patients With Metastatic Castration-resistant Prostate Cancer

To evaluate whether the efficacy of the abiraterone acetate tablets (I) is comparable to that of the ZYTIGA) by comparing the serum testosterone concentrations on Day 9 and/or Day 10 after oral administration of the two formulations in patients with metastatic castration-resistant prostate cancer (mCRPC).

Fudan University Shanghai Cancer Center
 (2.3 away) Contact site
  • 0 views
  • 16 May, 2021
  • 1 location
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer

The purpose of this study is to evaluate the effectiveness of niraparib in combination with abiraterone acetate plus prednisone (AAP) compared to AAP and placebo.

Huashan Hospital Fudan University
 (1.7 away) Contact site
  • 498 views
  • 31 Jul, 2021
  • +487 other locations
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

antiandrogen therapy
androgen suppression
apalutamide
cancer
metastasis
Fudan University Shanghai Cancer Center
 (2.3 away) Contact site
  • 291 views
  • 01 Aug, 2021
  • +354 other locations
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency. The intention of the study is to demonstrate that in participants with mHSPC, the …

Research Site
 (3.5 away) Contact site
  • 109 views
  • 15 Jul, 2021
  • +279 other locations