Shanghai City, China Clinical Trials

A listing of Shanghai City, China clinical trials actively recruiting patients volunteers.

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Found 1223 clinical trials
Sublobar Resection Versus Lobectomy for cT1N0M0 Non-small-cell Lung Cancer

The incidence rate of ground-glass opacity (GGO) has been increasing these years. A great number of retrospective studies suggested that sublobar resection was better for some GGO patients. However, no prospective clinical study supports the perspective. This study is prospective, multi-center, randomized-controlled. The aim of this study is to investigate …

lung carcinoma
Shanghai Zhongshan Hospital
 (2.3 away) Contact site
  • 0 views
  • 22 Jan, 2021
  • 1 location
A Comparison of Four Different Treatment Regimens of Helicobacter Pylori in Chinese Children

With the resistance of Helicobacter pylori increasing, low and unsatisfactory eradication rate (64%) have been observed with standard triple therapy in European children. Which regimen is appropriate for Chinese children? There is no large scale, multi center studies in China about treatment, CYP2C19 gene polymorphism, resistance rate and resistance genotype. …

Children's hospital of Fudan university
 (7.0 away) Contact site
  • 9 views
  • 21 Mar, 2021
  • 1 location
Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer

Adjuvant chemotherapy has been widely adopted worldwide for locally advanced colon cancer. However, more and more studies have found better efficacy and potential advantages of perioperative or neoadjuvant chemotherapy. The sooner the systemic chemotherapy is received, the better suppression it has on activity of tumor growth factors. Pre-operative chemotherapy may …

Department of Colorectal Surgery Fudan University Shanghai Cancer Center
 (2.3 away) Contact site
  • 3 views
  • 21 Jan, 2021
  • 1 location
ICSI Versus Conventional IVF in Couples With Non-severe Male Infertility

A multicenter, parallel-controlled(1:1 treatment ratio), open-label, randomized clinical trials regarding fertilization and pregnancy outcomes between ICSI and conventional IVF among couples with no-severe male-factor infertility in China.

intracytoplasmic sperm injection
sperm concentration
International Peace Maternity and Child Health Hospital of Shanghai Jiao Tong University
 (0.0 away) Contact site
  • 50 views
  • 13 May, 2021
  • +9 other locations
A Phase III Clinical Study of Napabucasin (GB201) Plus FOLFIRI in Adult Patients With Metastatic Colorectal Cancer

This is a randomized, open-label, multi-center, phase III study of Napabucasin plus bi-weekly FOLFIRI (Arm 1) vs. Napabucasin (Arm 2) for adult patients with metastatic CRC who have failed standard chemotherapy regimens. For patients who have failed bevacizumab with irinotecan-based chemotherapies (treatment failure is defined as radiologic progression of disease …

Shanghai General Hospital
 (1.9 away) Contact site
  • 27 views
  • 23 Jan, 2021
  • +36 other locations
A Safety Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

A randomized withdrawal study in which responders to open-label treatment with tofacitinib will be randomized in a 1:1 ratio to tofacitinib or placebo in a double-blind phase. In the double-blind phase "time to sJIA flare" will be evaluated as primary endpoint and subjects will be discontinued once they experience sJIA …

Children's Hospital of Fudan University
 (7.0 away) Contact site
  • 134 views
  • 02 Aug, 2021
  • +100 other locations
Survival Study of the Recombinant Human Neuregulin-1 in Subjects With Chronic Heart Failure.

The purpose of this study is to evaluate efficacy of rhNRG-1 in reducing the death rate of heart failure subjects with baseline NT-proBNP level between 600 pg/ml and 1700 pg/mL and NYHA class II to III.

nt-probnp
systolic heart failure
ejection fraction
Shanghai Oriental hospital
 (0.0 away) Contact site
  • 39 views
  • 01 May, 2021
  • +93 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-[L]1) agent …

vinflunine
adjuvant chemotherapy
advanced urothelial carcinoma
transitional cell carcinoma
growth factor
Renji Hospital, Shanghai Jiaotong University School of Medicine
 (3.5 away) Contact site
  • 271 views
  • 01 Aug, 2021
  • +592 other locations
A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

The purpose of this study to confirm the selexipag starting dose(s), selected based on pharmacokinetic (PK) extrapolation from adults, that leads to similar exposure as adults doses in children from greater than or equal to (>=) 2 to less than () 18 years of age with Pulmonary Arterial Hypertension (PAH), …

right heart catheterization
hypertension
endothelin
hpah
endothelin receptor antagonist
Shanghai Children's Medical Center
 (3.5 away) Contact site
  • 34 views
  • 18 Jul, 2021
  • +93 other locations
A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

This is a Phase III, randomised, double-blind, placebo-controlled, multicentre study assessing the efficacy and safety of durvalumab compared with placebo, as consolidation therapy in patients with locally advanced, unresectable, non-small cell lung cancer (Stage III), who have not progressed following definitive, platinum-based, chemoradiation therapy.

chemoradiotherapy
lung carcinoma
durvalumab
Research Site
 (93.2 away) Contact site
  • 284 views
  • 15 Jun, 2021
  • +146 other locations