Shanghai City, China Clinical Trials

A listing of Shanghai City, China clinical trials actively recruiting patients volunteers.

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Found 1289 clinical trials
A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

The purpose of the study is to evaluate on-treatment efficacy against hepatitis D virus (HDV) of JNJ-73763989 + nucleos(t)ide analog (NA) regimen compared to NA alone.

Huashan Hospital Fudan University
 (1.7 away) Contact site
  • 0 views
  • 12 Sep, 2021
  • +70 other locations
KN046 in Subjects With Advanced Squamous Non-small Cell Lung Cancer

This study is a randomized, double-blind, multicenter, phase III clinical study to compare the clinical efficacy and safety of KN046 plus paclitaxel and carboplatin versus placebo plus paclitaxel and carboplatin in subjects with advanced squamous NSCLC who have not previously received systemic treatment.

Shanghai Pulmonary Hospital
 (0.0 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • 1 location
A Study to Compare the Similarity in Efficacy and Safety Between TRS003 and China-approved Bevacizumab in NSCLC

This is a double-blind Phase 3 clinical trial evaluating the efficacy and safety of TRS003 and paclitaxel-carboplatin versus China-approved bevacizumab and paclitaxel-carboplatin in patients with unresectable, locally advanced, or metastatic non-squamous non-small cell lung cancer (NSCLC). Approximately 608 patients will be enrolled in this study from America, Europe, and Asia. …

Shanghai East Hospital
 (0.0 away) Contact site
  • 0 views
  • 25 Jan, 2021
  • +9 other locations
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy Compared With Carboplatin-Pemetrexed in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

The purpose of this study is to compare the efficacy, as demonstrated by progression-free survival (PFS), in participants treated with amivantamab in combination with chemotherapy, versus chemotherapy alone in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) characterized by EGFR Exon 20ins mutations.

pemetrexed
cancer chemotherapy
measurable disease
EGFR
epidermal growth factor receptor
Fudan University Shanghai Cancer Center
 (2.3 away) Contact site
  • 1 views
  • 22 Sep, 2021
  • +289 other locations
A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

This study aims to define the efficacy and safety of inebilizumab for the prevention of flare of IgG4-related disease (IgG4-RD).

Viela Bio Investigative Site
 (0.0 away) Contact site
  • 0 views
  • 19 Aug, 2021
  • +85 other locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

osimertinib
cancer treatment
measurable disease
stage iv non-small cell lung cancer
EGFR
Ruijin Hospital, Shanghai Jiao Tong University
 (1.1 away) Contact site
  • 30 views
  • 22 Sep, 2021
  • +341 other locations
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low Hormone Receptor Positive Metastatic Breast Cancer

This study will evaluate the efficacy, safety and tolerability of trastuzumab deruxtecan compared with investigator's choice chemotherapy in human epidermal growth factor receptor (HER)2-low, hormone receptor (HR) positive breast cancer patients whose disease has progressed on endocrine therapy in the metastatic setting.

Research Site
 (2.3 away) Contact site
  • 37 views
  • 22 Sep, 2021
  • +277 other locations
Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2)

ENCHANTED2 is an international, multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to assess different approaches to manage blood pressure (BP) in acute ischemic stroke (AIS) patients who have undergone mechanical thrombectomy (MT). There are two nested substudies evaluating different approaches to secondary prevention in this high-risk stroke population.

Shanghai Changhai Hospital
 (0.1 away) Contact site
  • 0 views
  • 25 Jan, 2021
  • 1 location
Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

This is a Phase 3 open-label, multicenter, randomized, active-controlled study designed to compare the efficacy and safety and tolerability of P1101 compared with ANA after 12 months of treatment as second-line therapy for subjects with ET who have had a suboptimal or failed response to HU.

thrombocytosis
hydroxyurea
anagrelide
interferon
platelet count
Ruijin Hospital affiliated to Shanghai Jiao Tong University school of Medicine
 (0.0 away) Contact site
  • 0 views
  • 20 Mar, 2021
  • +50 other locations
A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

This study will evaluate the efficacy and safety of CBP-307 in subjects with moderate to severe ulcerative colitis (UC).

Connect Investigative Site 2011
 (1.1 away) Contact site
  • 4 views
  • 22 May, 2021
  • +76 other locations