Jurong, China
Neoadjuvant Chemotherapy in Combination With Toripalimab for HR+/HER2- Breast Cancer : a Randomized, Open-label, Parallel-controlled, Multi-center Phase III Study (NEOTORCH-BREAST04)
Phase
3Span
261 weeksSponsor
First Affiliated Hospital of Zhejiang UniversityZhengzhou
Recruiting
Zhengzhou, Henan
Recruiting
Efficacy, Safety, Pharmacokinetics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis
Phase
3Span
102 weeksSponsor
Beijing InnoCare Pharma Tech Co., Ltd.Zhengzhou, Henan
Recruiting
To Evaluate the Clinical Study of GS1191-0445 Injection in the Treatment of Hemophilia A
Phase
3Span
296 weeksSponsor
Gritgen Therapeutics Co., Ltd.Zhengzhou, Henan
Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903
Phase Ia is divided into two phases of dose escalation and dose extension: This part includes dose escalation and dose extension of RP903 single agent to investigate the safety, tolerability, maximum tolerated dose and pharmacokinetic (PK) characteristics of RP903 single agent. Phase Ib is the clinical indication expansion phase, and the primary purpose of this phase is to evaluate the initial safety and anti-tumor efficacy in a selected indication target population. After determining RP903 monotherapy RP2D in Phase Ia, SMC will select four advanced malignant tumors with PIK3CA mutations (cervical cancer, endometrial cancer, breast cancer, and ovarian cancer) as indications for clinical expansion studies based on phase Ia efficacy, safety, and pharmacokinetic (PK) data. The dose was determined according to the results of the dose escalation phase and the dose extension phase.
Phase
1Span
160 weeksSponsor
Risen (Suzhou) Pharma Tech Co., Ltd.Zhengzhou
Recruiting
Clinical Trial of TQB2825 Injection Combined Immunochemotherapy in Subjects With Diffuse Large B Cell Lymphoma
Phase
1/2Span
89 weeksSponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Zhengzhou, Henan
Recruiting
Reinforcement Learned Automatic Anesthesia System During Painless Gastrointestinal Endoscopy
Phase
N/ASpan
22 weeksSponsor
Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.Zhengzhou, Henan
Recruiting
Healthy Volunteers
Standardized Procedure for Intracranial Drug-Eluting Stenting in the Treatment of Intracranial Atherosclerotic Stenosis
The investigation is a prospective, multi-center clinical study. The trial is expected to enroll 300 subjects. The population for this study is subjects with intracranial atherosclerotic stenosis who are suitable candidates for stent angioplasty. Patients fulfilling all of the inclusion criteria and none of the exclusion criteria will be enrolled after they signed the informed consent form. The study consists of ten visits including preoperative screening, procedure date, 30 days, 3, 6 months, 1, 2, 3, 4 years and 5 years. The primary endpoints are stroke or death within 30 days after enrollment, plus any ischemic stroke or revascularization from the original culprit intracranial artery beyond 30 days through 12 months after procedure.
Phase
N/ASpan
118 weeksSponsor
Sino Medical Sciences Technology Inc.Zhengzhou
Recruiting
Clinical Trial of TQB2825 Injection Combined With Chemotherapy in Subjects With Diffuse Large B-cell Lymphoma
Phase
2Span
155 weeksSponsor
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.Zhengzhou, Henan
Recruiting
Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung Cancer
Phase
2Span
108 weeksSponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Zhengzhou, Henan
Recruiting