West Vancouver, Canada Clinical Trials

A listing of West Vancouver, Canada clinical trials actively recruiting patients volunteers.

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Found 122 clinical trials
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C2541013 MIRNA NASH  

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

GI Research Institute
 (4.3 away)
  • 275 views
  • 30 Jul, 2021
  • +64 other locations
featured
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
British Columbia Cancer Agency
 (5.4 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +40 other locations
featured
COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 – Canada  

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements.   This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept …

epoetin alfa
Vancouver General Hospital
 (4.7 away)
  • 33 views
  • 03 Aug, 2021
  • +9 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-[L]1) agent …

advanced urothelial carcinoma
renal function
erdafitinib
docetaxel
growth factor
Vancouver Cancer Centre
 (5.5 away) Contact site
  • 271 views
  • 01 Aug, 2021
  • +592 other locations
Field Randomization of NA-1 Therapy in Early Responders

The purpose of this study is to determine whether NA-1 is effective in reducing global disability in patients with acute cerebral ischemia if administered early after symptom onset.

Vancouver General Hospital, Vancouver Coastal Health
 (5.4 away) Contact site
  • 29 views
  • 21 Jul, 2021
  • +3 other locations
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

bendamustine
acalabrutinib
rituximab
cyclin d1
Research Site
 (5.5 away) Contact site
  • 1270 views
  • 24 Jul, 2021
  • +250 other locations
Safety Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (DME)

This study is intended to assess the safety, tolerability and evidence of pharmacodynamic activity of a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME)

University of British Columbia
 (5.4 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +31 other locations
Efficacy Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy Compared With Placebo in Adult Patients With NASH and Liver Fibrosis.

Randomized, double-blind, parallel-group, multicenter study to assess efficacy, safety, and tolerability of oral tropifexor & licogliflozin combination therapy and each monotherapy, compared with placebo for treatment of adult patients with nonalcoholic steatohepatitis (NASH) and liver fibrosis

Novartis Investigative Site
 (4.3 away) Contact site
  • 27 views
  • 26 Jul, 2021
  • +95 other locations
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients in this study will have …

enfortumab vedotin
systemic therapy
carboplatin
pd-l1
transitional cell carcinoma
Site CA11006
 (5.5 away) Contact site
  • 5 views
  • 21 Jul, 2021
  • +111 other locations
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Dimethyl Fumarate or Fingolimod to Ofatumumab

The open label study to evaluate effectiveness of treatment with ofatumumab in patients transitioning from commonly used oral MS therapies - fingolimod or dimethyl fumarate, due to breakthrough disease.

fingolimod
dimethyl fumarate
ofatumumab
Novartis Investigative Site
 (9.0 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +116 other locations