Waterloo, Canada Clinical Trials

A listing of Waterloo, Canada clinical trials actively recruiting patients volunteers.

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Found 22 clinical trials
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (0.6 away) Contact site
  • 21 views
  • 04 Aug, 2021
  • +474 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

systemic therapy
arthritis
plaque psoriasis
risankizumab
apremilast
K. Papp Clinical Research /ID# 230336
 (0.6 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +61 other locations
CF101 Therapy in Patients With Moderate-to-severe Plaque Psoriasis

This trial will test the hypothesis that the administration of CF101, a novel anti-inflammatory agent, to patients with moderate to severe plaque psoriasis will relieve signs and symptoms of the disease. CF101 effect will be in comparison to apremilast in this study population

phototherapy
apremilast
serum pregnancy test
Gda skim Centrum Zdrowia
 (4167.9 away) Contact site
  • 26 views
  • 04 Aug, 2021
  • +45 other locations
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

plaque psoriasis
mirikizumab
K. Papp Clinical Research Inc
 (0.6 away) Contact site
  • 717 views
  • 27 Jul, 2021
  • +354 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

adjuvant chemotherapy
sentinel lymph node biopsy
endocrine therapy
hormone therapy
breast-conserving surgery
Grand River Regional Cancer Centre at Grand River Hospital
 (2.4 away) Contact site
  • 598 views
  • 25 Jul, 2021
  • +318 other locations
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

The study will evaluate the efficacy and safety of trastuzumab deruxtecan (also known as T-DXd, DS-8201a), either alone or in combination with pertuzumab, in treating patients with Human epidermal growth factor receptor 2 (HER2)-positive breast cancer as a first line of treatment.

Research Site
 (2.4 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +185 other locations
Study to Evaluate Adverse Events and Change in Disease Activity With Oral Tablets of Upadacitinib in Adult Participants With Non-Segmental Vitiligo

Vitiligo is a common chronic autoimmune disease that causes the body's immune system to attack its own pigment producing skin cells. This study is to evaluate how safe and effective upadacitinib is in participants with non-segmental vitiligo. Adverse effects and change in disease activity will be assessed. Upadacitinib is being …

K. Papp Clinical Research /ID# 228877
 (0.6 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +43 other locations
A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

hidradenitis
bimekizumab
antibiotics
abscess
Hs0004 50174
 (49.1 away) Contact site
  • 342 views
  • 04 Aug, 2021
  • +100 other locations
A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study assessing the activity of durvalumab and chemotherapy administered prior to surgery compared with placebo and chemotherapy administered prior to surgery in terms of pathological complete response.

durvalumab
lung carcinoma
carboplatin
gemcitabine
pemetrexed
Research Site
 (2.4 away) Contact site
  • 251 views
  • 31 Jul, 2021
  • +318 other locations
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab

The purpose of this extension study is to establish efficacy and safety of ligelizumab. This will be assessed in adult and adolescent chronic spontaneous urticaria (CSU) patients who have completed a preceding ligelizumab study and have relapsed, following treatment in these preceding studies, despite standard of care H1-antihistamine (H1-AH) treatment. …

ligelizumab
antihistamines
urticaria
Novartis Investigative Site
 (2.6 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +226 other locations