Ville Saint-Laurent, Canada Clinical Trials

A listing of Ville Saint-Laurent, Canada clinical trials actively recruiting patients volunteers.

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Found 235 clinical trials
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant …

CHUM - Hopital Notre-Dame
 (9.2 away) Contact site
  • 167 views
  • 22 Jul, 2021
  • +125 other locations
Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)

To evaluate the safety and efficacy of Zimura (complement factor C5 inhibitor) compared to Sham in subjects with autosomal recessive Stargardt disease 1 (STGD1).

Montreal Children's Hospital
 (7.5 away) Contact site
  • 114 views
  • 21 Jul, 2021
  • +40 other locations
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

The purpose of this study is to assess the safety and efficacy of pembrolizumab (MK-3475) combination therapy in patients with metastatic castrate resistant prostate cancer (mCRPC). There will be nine cohorts in this study: Cohort A will receive pembrolizumab + olaparib, Cohort B will receive pembrolizumab + docetaxel + prednisone, …

bone metastases
abiraterone
androgen suppression
luteinizing hormone
bone scan
Merck Canada
 (5.7 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +13 other locations
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

testosterone
ct scan
gonadotropin releasing hormone
abiraterone
androgen
Research Site
 (9.3 away) Contact site
  • 200 views
  • 23 Jul, 2021
  • +194 other locations
Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

A Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment and Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder Cancer

Research Site
 (9.4 away) Contact site
  • 147 views
  • 14 Jul, 2021
  • +264 other locations
Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

The purpose of this study is to evaluate the effect of treatment with omecamtiv mecarbil compared with placebo on exercise capacity as determined by cardiopulmonary exercise testing following 20 weeks of treatment with omecamtiv mecarbil or placebo

Mcgill University Health Centre (MUHC)-The Montreal General Hospital (MGH)
 (5.4 away) Contact site
  • 62 views
  • 09 Jul, 2021
  • +80 other locations
A Study of Biomarker-Directed Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)

This study will investigate the utility of biomarker-based triage for study participants with advanced non-small cell lung cancer (NSCLC) without prior systemic therapy. Study participants within groups defined by a biomarker-based classifier (gene expression profile [GEP] and tumor mutational burden [TMB]) will be randomized to receive pembrolizumab in combination with …

Jewish General Hospital ( Site 0307)
 (5.8 away) Contact site
  • 352 views
  • 21 Jul, 2021
  • +92 other locations
Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Sometimes, cancer patients receive an initial treatment, followed by additional treatment to lower the chance of cancer coming back. The standard or usual treatment for this type of disease is initially having radiation therapy at the same time as chemotherapy (with a drug called cisplatin), with no additional therapy afterwards

neutrophil count
human papillomavirus
x-rays
pet/ct scan
treatment schedule
The Jewish General Hospital
 (5.8 away) Contact site
  • 56 views
  • 21 Jul, 2021
  • +29 other locations
ADCC Mediated B-Cell dEpletion and BAFF-R Blockade

VAY736 dose testing; VAY736 efficacy and safety testing.

adcc
Novartis Investigative Site
 (9.4 away) Contact site
  • 83 views
  • 21 Jul, 2021
  • +59 other locations
A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

The purpose of this study to confirm the selexipag starting dose(s), selected based on pharmacokinetic (PK) extrapolation from adults, that leads to similar exposure as adults doses in children from greater than or equal to (>=) 2 to less than () 18 years of age with Pulmonary Arterial Hypertension (PAH), …

hypertension
hpah
connective tissue disease
endothelin
endothelin receptor antagonist
Centre Hospitalier Sainte Justine
 (6.1 away) Contact site
  • 34 views
  • 18 Jul, 2021
  • +93 other locations