Vaughan, Canada Clinical Trials

A listing of Vaughan, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 15 clinical trials
Featured trial
Caregiver-Provided Life Review for Persons with Dementia

This study, Caregiver-Provided Life Review (C-PLR) is created based on Life Review therapy. It is for persons living with early-stage dementia along with mild depressive symptoms who are 65 years or older, community-dwellers or the residents of senior housing, independent or assisted living facilities conducted by their family members (18 …

depression
Accepts healthy volunteers
Online studies
dementia
Online Study Center
(online study) Contact site
  • 566 views
  • 09 Aug, 2022
  • 1 location
  • Online study
Dupilumab for the Treatment of Chronic Inducible Cold Urticaria in Patients Who Remain Symptomatic Despite the Use of H1-antihistamine (LIBERTY-CINDU CUrIADS)

Primary Objective: To demonstrate the efficacy of dupilumab in adult and adolescent participants with primary acquired chronic inducible cold urticaria (ColdU) who remain symptomatic despite the use of an H1-antihistamine Secondary Objectives: To demonstrate the efficacy of dupilumab on primary acquired chronic inducible ColdU disease control To demonstrate the efficacy …

Investigational Site Number :1240001
 (9.3 away) Contact site
  • 58 views
  • 10 Aug, 2022
  • +29 other locations
RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)

To evaluate the treatment effect of seladelpar on composite biochemical improvement in cholestasis markers based on ALP and total bilirubin and to evaluate the safety of seladelpar over 12 months of treatment compared to placebo

Toronto Digestive Disease Associates Inc
 (5.0 away) Contact site
  • 5 views
  • 08 Aug, 2022
  • +157 other locations
A Study of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis (SUMMIT)

The purpose of the study is to evaluate the efficacy of an oral tablet formulation of JNJ-77242113 compared with placebo in participants with moderate-to-severe plaque psoriasis.

Toronto Research Centre
 (6.9 away) Contact site
  • 0 views
  • 11 Aug, 2022
  • +19 other locations
Study of ARO-APOC3 in Adults With Mixed Dyslipidemia (MUIR)

Participants who have met all protocol eligibility criteria will be randomly assigned to treatment (ARO-APOC3 or placebo) in a double-blind fashion and will be evaluted for safety and efficacy over 48 weeks. Participants will be counseled to remain on a specified diet throughout the study, as recommended by the Investigator …

LMC Diabetes & Endocrinology
 (3.9 away) Contact site
  • 0 views
  • 09 Aug, 2022
  • +30 other locations
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.

Canadian Phase Onward Inc
 (5.2 away) Contact site
  • 6 views
  • 10 Aug, 2022
  • +40 other locations
A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence

The purpose of the study is to evaluate the safety and effects of onabotulinumtoxinA (BOTOX) for the temporary improvement in the appearance of platysma prominence. Study doctors will randomize participants into 1 of the 2 groups, called treatment arms. There is a 1 in 2 chance that a participant will …

The Center For Dermatology /ID# 229481
 (5.3 away) Contact site
  • 179 views
  • 10 Aug, 2022
  • +28 other locations
TRILUMINATE Pivotal Trial

The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or greater estimated risk for mortality or morbidity with tricuspid valve surgery. This randomized controlled trial will …

regurgitation
medical therapy
repair of tricuspid valve
tricuspid valve repair
diuretics
Sunnybrook Health Science Centre
 (9.8 away) Contact site
  • 156 views
  • 10 Aug, 2022
  • +79 other locations
A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older (EVERGREEN)

The study will enroll up to 27,500 participants in order to demonstrate the efficacy of the active Ad26.RSV.preF-based study vaccine in the prevention of Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed Respiratory Syncytial Virus (RSV)-mediated Lower Respiratory Tract Disease (LRTD) when compared to placebo in adults aged 60 years and …

Accepts healthy volunteers
LMC Clinical Research dba Manna Research Inc. Toronto
 (8.1 away) Contact site
  • 46 views
  • 11 Aug, 2022
  • +254 other locations
A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a study to demonstrate the effect of oral ozanimod as maintenance therapy in participants with moderately to severely active Crohn's Disease.

crohn's disease
remission
abdominal pain
Toronto Digestive Disease Associates Inc
 (5.0 away) Contact site
  • 987 views
  • 10 Aug, 2022
  • +479 other locations