Trois-Rivieres, Canada Clinical Trials

A listing of Trois-Rivieres, Canada clinical trials actively recruiting patients volunteers.

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Found 22 clinical trials
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

Research Site
 (1.6 away) Contact site
  • 0 views
  • 24 Jul, 2021
  • +116 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

stiffness
methotrexate
antirheumatics
rheumatism
Ctr. de Recherche Musculo-Sque /ID# 227824
 (1.6 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +292 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

bypass graft
iron
nesiritide
natriuretic peptide
nt-probnp
Centre Int gr Universitaire de Sant et de Services Sociaux de la Mauricie-et-du-centre-du-Quebec
 (1.0 away) Contact site
  • 5316 views
  • 02 Aug, 2021
  • +365 other locations
Myocardial Ischemia and Transfusion

The purpose of this study is to compare two red blood cell transfusion strategies (liberal and restrictive) for patients who have had an acute myocardial infarction and are anemic.

acute myocardial infarction
myocardial infarction
ischemia
stemi
red blood cell transfusion
General Hospital Trois-Rivi rs
 (2.1 away) Contact site
  • 385 views
  • 31 Jul, 2021
  • +132 other locations
A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC MK-7339-008/KEYLYNK-008)

The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, vs. pembrolizumab plus maintenance olaparib placebo for the treatment of squamous NSCLC. The study's 2 primary hypotheses are: Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus maintenance olaparib placebo with respect to progression-free survival (PFS) per RECIST 1.1 by …

CIUSSS de la Mauricie et du Centre du Quebec ( Site 0106)
 (1.0 away) Contact site
  • 119 views
  • 04 Aug, 2021
  • +202 other locations
A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Assessment of PF-06700841 in participants with moderate to severe active, generalized Systemic Lupus Erythematosus (SLE) that have inadequate response to standard of care.

methotrexate
corticosteroids
lupus
antimalarials
mycophenolate
Centre de Recherche Musculo-Squelettique
 (1.6 away) Contact site
  • 198 views
  • 04 Aug, 2021
  • +224 other locations
Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) versus placebo in combination with neoadjuvant (pre-surgery) chemotherapy and adjuvant (post-surgery) endocrine therapy in the treatment of adults who have high-risk early-stage estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer. The primary …

EGFR
epidermal growth factor receptor
paclitaxel
progesterone
doxorubicin
Centre Hospitalier Regional de Trois-Rivieres ( Site 0106)
 (1.0 away) Contact site
  • 188 views
  • 04 Aug, 2021
  • +286 other locations
A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis

This study consists of two periods. The objective of Period 1 is to evaluate the efficacy of upadacitinib in combination with a 26-week corticosteroid (CS) taper regimen compared to placebo in combination with a 52-week CS taper regimen, as measured by the proportion of participants in sustained remission at Week …

Ctr. de Recherche Musculo-Sque /ID# 201224
 (1.6 away) Contact site
  • 311 views
  • 01 Aug, 2021
  • +302 other locations
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sj gren's Syndrome

This study will evaluate safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of CFZ533 (iscalimab) in patients with Sjgren's Syndrome.

fatigue
Novartis Investigative Site
 (1.6 away) Contact site
  • 100 views
  • 26 Jul, 2021
  • +74 other locations
Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are na ve to Intolerant of or Incomplete Responders to Omalizumab

Primary Objective: To demonstrate the efficacy of dupilumab in study participants with CSU who remain symptomatic despite the use of H1 antihistamine (Study A: omalizumab nave; Study B: omalizumab intolerant or incomplete responders) Secondary Objectives: To demonstrate the efficacy of dupilumab on urticaria activity composite endpoint and itch or hives, …

omalizumab
urticaria
h1 antihistamine
corticosteroids
dupilumab
Investigational Site Number 1240006
 (2.6 away) Contact site
  • 10 views
  • 04 Aug, 2021
  • +83 other locations