Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

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Found 20 clinical trials
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Dupilumab Asthma Sleep Study

Primary Objective: To assess the effect of dupilumab on sleep Secondary Objectives: To evaluate the effect of dupilumab on additional patient reported sleep outcomes To evaluate the effect of dupilumab on objective sleep assessment To evaluate the effect of dupilumab on asthma symptoms To evaluate the effect of dupilumab on …

fractional exhaled nitric oxide
nitric oxide
pulmonary function test
forced expiratory volume
eosinophil count
Investigational Site Number :1240005
 (10.1 away) Contact site
  • 114 views
  • 21 Jan, 2022
  • +91 other locations
None
Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept

Objective: To determine the association between baseline aqueous cytokine levels and treatment intervals for patients under a variable dosing regimen with intravitreal aflibercept in patients with neovascular age-related macular degeneration (nAMD), macular edema secondary to retinal vein occlusion (RVO) and diabetic macular edema (DME). Methods: A prospective, single-centre study will …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 07 May, 2021
  • +1 other locations
None
Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab

Objective: To determine the association between baseline aqueous cytokine levels and treatment intervals for patients under a variable dosing regimen with intravitreal ranibizumab in patients with neovascular age-related macular degeneration (nAMD), macular edema secondary to retinal vein occlusion (RVO) and diabetic macular edema (DME). Methods: A prospective, single-centre study will …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 08 May, 2021
  • +1 other locations
None
Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery

During glaucoma surgery, a new opening is created that allows fluid to drain out of the eye, bypassing the clogged drainage channels that are malfunctioning in patients with glaucoma. In some patients who have had glaucoma surgery too much fluid flows out and this results in a pressure that is …

brimonidine tartrate ophthalmic solution
trabeculectomy
drainage
treatment of glaucoma
glaucoma
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 2 views
  • 22 Feb, 2021
  • +1 other locations
None
A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy

This is a multicenter, randomized, open label study with blinded outcome assessment to evaluate the impact of additional/intensive LDL-cholesterol reduction with evolocumab on carotid artery atherosclerotic plaques in higher risk subjects with severe asymptomatic but vulnerable plaques.

total cholesterol
endarterectomy
simvastatin
diabetes
peripheral artery disease
North York Diagnostic and Cardiac Centre
 (7.1 away) Contact site
  • 0 views
  • 30 Sep, 2021
  • +1 other locations
None
Factor In the Initial Resuscitation of Severe Trauma 2 Patients

Injury is the leading cause of death for people between the ages of 1-44. This is especially true in trauma patients who have bleeding complications. Acute trauma coagulopathy (ATC) is associated with high transfusion requirements, longer ICU stays, and a greater incidence of multi-organ dysfunction. The cause of coagulopathy is …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 18 Oct, 2021
  • +3 other locations
None
Adjunct Treatment With Cariprazine for Adults With Attention-deficit/Hyperactivity Disorder

According to the Canadian ADHD Practice Guidelines, psychostimulants are the preferred treatment of attention-deficit/hyperactivity disorder (ADHD), especially for those that require urgent care. Specifically, long-acting psychostimulants are considered the gold-standard pharmacological treatment for ADHD. Using extended-release formulations, long-acting psychostimulants provide an extended duration of daily symptom relief in addition to …

antipsychotics
psychotherapy
hyperactivity
START Clinic for Mood and Anxiety Disorders
 (10.0 away) Contact site
  • 0 views
  • 19 Dec, 2021
  • 1 location
None
Empagliflozin and Cardiac Remodelling in People Without Diabetes

The purpose of this study is to evaluate the effects of empagliflozin on cardiac structure, function and circulating biomarkers in patients with cardiovascular risk factors, but without diabetes. Empagliflozin is an antihyperglycemic agent approved by Health Canada and the FDA for the treatment of type 2 diabetes. Previous post-marketing clinical …

myocardial infarction
heart failure
heart disease
infarct
antihypertensive drugs
North York Diagnostic and Cardiac Centre
 (7.1 away) Contact site
  • 0 views
  • 26 Jun, 2021
  • +3 other locations
None
PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercept

The presence of PEDs in nAMD, CSR and iPCV can present a diagnostic challenge in the elderly population; despite detailed diagnostic testing to differentiate these three conditions, misdiagnosis and mistreatment still occurs. One potential way of differentiating these three conditions might be to compare cytokine profiles in nAMD versus CSR …

Sunnybrook Research Institute
 (7.2 away) Contact site
  • 0 views
  • 03 Feb, 2021
  • 1 location
None
Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome

The TILE pilot study will be a multicenter, open-label, assessor-blinded RCT (randomized control trial) comparing extended LMWH (Low Molecular Weight Heparin) vs. DOAC (Direct Oral Anticoagulants) to PTS (prevent post thrombotic syndrome) in patients with DVT (Deep Vein Thrombosis).

clot
heparin
tinzaparin
blood clot
rivaroxaban
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 19 Jan, 2022
  • +2 other locations