Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 404 clinical trials
Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging

Bladder cancer is the fifth most common cancer in Canada and there has been relatively little progress in altering its clinical course over the last three decades. One of the major problems identified in the management of this disease, is under staging of muscle invasive disease which can lead to …

Sunnybrook Odette Cancer Centre
 (7.2 away) Contact site
  • 14 views
  • 26 Jan, 2021
  • +5 other locations
Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM

The purpose of this study is to evaluate the safety and feasibility of the Exablate Model 4000 Type 2 system when used as a tool to open the blood-brain-barrier (BBB) in subjects with recurrent glioblastoma (rGBM) undergoing carboplatin monotherapy.

glioblastoma multiforme
tumor progression
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 01 Jun, 2021
  • +1 other locations
Measuring Fluid Flow in the Brain Using Alcohol and MRI in Healthy Participants

Intracranial interstitial fluid (ISF) flow is crucial for adequate clearance of extracellular waste products from the brain parenchyma. Recent demonstrations have shown that a deficiency in flow leads to the accumulation of such waste products in neurodegenerative disorders. Unfortunately, no clinical investigation that gives a quantitative measure of ISF flow …

Sunnybrook Research Institute
 (7.2 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • 1 location
Deep Brain Stimulation for Treatment Resistant Depression

Treatment resistant depression (TRD) is a major global health concern, and there is a crucial need to develop novel effective treatments. The medial forebrain bundle (MFB) is a recently described DBS target, with reported rapid onset of antidepressant effects. A recent small randomized trial reported a 100% response rate. The …

depressed
brain stimulation
antidepressants
psychotherapy
depressive disorder
Sunnybrook Health Sciences Center
 (7.2 away) Contact site
  • 3 views
  • 25 Mar, 2021
  • 1 location
Pneumatic Retinopexy for Primary Rhegmatogenous Retinal Detachment: To Steamroll or Not

This is a randomized controlled trial comparing displacement of macula and the rapidity of reattachment of macula between two different positioning techniques after pneumatic retinopexy : Direct technique (patient is positioned so that the bubble is immediately placed directly over the retina break) and Steamroller technique (patient is initially positioned …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 29 Jan, 2021
  • 1 location
A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor

This study will be a single-centre, prospective, single-arm, open-label, 12-week pilot trial assessing the safety and preliminary efficacy of a second MR-guided focused ultrasound (MRgFUS) thalamotomy on the nave brain hemisphere after 48 weeks or more of the first MRgFUS thalamotomy in patients with medication-refractory ET. This study will be …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 02 Feb, 2021
  • 1 location
Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria

Objective: To compare outcomes of retinal detachment repair following pneumatic retinopexy (PnR) versus pars plana vitrectomy in terms of anatomical success, functional success and patient quality of life in patients with extended criteria. Methods: A prospective, randomized, controlled trial will be conducted with 178 patients presenting at St. Michael's Hospital …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 23 Jan, 2021
  • +1 other locations
Increasing Access to Evidence-based Treatments for Depression

The goal of this single-blind, randomized controlled pilot study is to evaluate the acceptability and feasibility of an Interpersonal Psychotherapy (IPT) asynchronous self-directed digital training platform for psychiatry residents, as compared to synchronous large group online workshop teaching. This study has the potential to improve access to competency-based training and …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 34 views
  • 26 Jan, 2021
  • +3 other locations
Phase 2B Study to Evaluate the Efficacy of PB2452 in Reversal of Ticagrelor in Subjects Aged 50-80 Years Old

This phase 2B study is a multi-center, randomized, double-blind, placebo-controlled study. The study is designed to evaluate the efficacy of PB2452 in reversing the anti-platelet effects of ticagrelor as part of a dual antiplatelet regimen and to evaluate the safety and tolerability of PB2452 in subjects aged 50-80 years old. …

BioPharma Services Inc.
 (6.4 away) Contact site
  • 0 views
  • 15 Jul, 2021
  • +14 other locations
Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)

Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for bilateral LPI. Our null hypothesis is that there is no difference in dysphotopsia or pain levels by LPI position. …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 15 Feb, 2021
  • 1 location