Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 388 clinical trials
Promoting Reengagement in Daily Meaningful Activity Intervention for adults with mild cognitive impairment and their caregivers

The PRIMA project is design to help persons with mild cognitive impairment to help them to improve their engagement in personally meaningful activity and improve their overall quality of life with their family caregivers support. The goal of PRIMA project is to increase persons with mild cognitive impairment’s engagement in …

Online studies
Accepts healthy volunteers
Online Study Center
(online study) Contact site
  • 371 views
  • 23 Sep, 2022
  • 1 location
  • Online study
Objective, Passive Assessment of LRRK2 Carriers (OPAL)

This study is currently only open to active participants in the University of Rochester’s VALOR-PD study. The goal of this project is to identify objective, sensitive, and convenient measures for assessing early signs of Parkinson's disease in an at-risk population at home. We will do so by using a wireless …

Online studies
movement disorder
University of Rochester
(online study) Contact site
  • 64 views
  • 12 May, 2022
  • 1 location
  • Online study
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab (ARTIOS)

Open-label study to evaluate the effectiveness of treatment with ofatumumab in subjects transitioning from any fumarate-based RMS approved therapy or fingolimod due to breakthrough disease.

ofatumumab
fingolimod
dimethyl fumarate
Novartis Investigative Site
 (7.2 away) Contact site
  • 183 views
  • 12 Jul, 2022
  • +136 other locations
PSMA-PET Registry for Recurrent Prostate Cancer (PREP)

This study aims to institute a province-wide registry leveraging the availability of a new Positron Emission Tomography tracer, [18F]-DCFPyL and PET expertise across Ontario centers to improve our ability to characterize patterns of recurrence and personalize therapies in men with recurrent prostate cancer after primary treatment.

karnofsky performance status
positron emission tomography
prostatectomy
bone scan
ct scan
Toronto Sunnybrook Cancer Centre
 (7.2 away) Contact site
  • 108 views
  • 15 Feb, 2022
  • +5 other locations
SAHaRA: A Randomized Controlled Trial

The SAHaRA trial will clarify the role of treating anemia with Red Blood Cell (RBC) transfusion in a unique and vulnerable patient population, and determine whether that impacts on functional outcomes and mortality. It will guide best practice standards and clarify the optimal RBC transfusion strategy in patients with aSAH.

Sunnybrook Research Institute
 (7.2 away) Contact site
  • 364 views
  • 02 Mar, 2022
  • +16 other locations
RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy (BREVITY)

The current study aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsies taken starting from 35 +/- 4 days after the initiation of neoadjuvant chemotherapy.

invasive breast cancer
breast cancer
cancer
adjuvant therapy
Sunnybrook Health Sciences Center
 (7.2 away) Contact site
  • 33 views
  • 09 Jul, 2022
  • +5 other locations
A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm tested and to identify recommended doses and regimens for future studies.

Novartis Investigative Site
 (7.2 away) Contact site
  • 86 views
  • 17 Jun, 2022
  • +17 other locations
Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM

The purpose of this study is to evaluate the safety and feasibility of the Exablate Model 4000 Type 2 system when used as a tool to open the blood-brain-barrier (BBB) in subjects with recurrent glioblastoma (rGBM) undergoing carboplatin monotherapy.

tumor progression
glioblastoma multiforme
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 14 views
  • 15 Dec, 2021
  • +3 other locations
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR). This evaluation will provide information that brolucizumab is non-inferior to PRP with respect to the change in best corrected visual acuity at Week …

Novartis Investigative Site
 (7.2 away) Contact site
  • 13 views
  • 01 Jul, 2022
  • +75 other locations
Initial Vancomycin Taper for the Prevention of Recurrent Clostridium Difficile Infection (TAPER-V)

The first line therapy for an initial episode of CDI (Clostridium difficile infection) is 10-14 days of oral vancomycin which is now recommended over metronidazole in the 2018 guidelines from the Association of Medical Microbiologists and Infectious Diseases of Canada (AMMI). Although response rates for the treatment of a first …

Sunnybrook Health Science Centre
 (7.2 away) Contact site
  • 0 views
  • 19 Apr, 2022
  • +2 other locations