Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

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Found 179 clinical trials
Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS)

This study is a multi-center, open-label study of intravenous (IV) ANX005 in participants with ALS.

primary lateral sclerosis
weakness
Annexon Investigational Site 09
 (7.2 away) Contact site
  • 62 views
  • 04 Oct, 2022
  • +10 other locations
Function, Pain, and Alignment Following Knee Replacement for the Treatment of Osteoarthritis

There are many factors that can influence patient satisfaction and patient related outcomes following total knee replacement including the surgical alignment of the joint components. Historically, total knee replacements have been performed with an aim aiming to achieve neutral alignment or a mechanical weight axis in the lower extremity . …

North York General Hospital
 (5.5 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer (USmBRT-B)

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

carcinoma
breast cancer staging
advanced breast cancer
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
Fecal Microbial Transplantation Non-Small Cell Lung Cancer and Melanoma (FMT-LUMINATE)

The aim of this study is to assess the anti-tumor activity of FMT administered in combination with ICI therapy.

Sunnybrook Health Sciences Centre/Sunnybrook Research Institute
 (7.2 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +3 other locations
A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy

The purpose of this study is to determine whether CVL-871 is safe and tolerable in patients with Dementia-Related Apathy and if CVL-871 shows changes in clinical measurements of apathy.

Toronto, Ontario
 (7.2 away) Contact site
  • 8 views
  • 07 Oct, 2022
  • +21 other locations
Love Together, Parent Together: A Protocol for a Pilot Study of an Intervention for Interparental Couples With Young Children (L2P2)

The COVID-19 pandemic has created a population-level threat to social relationships that requires a population-level solution. Among those who are particularly vulnerable to heightened conflict are interparental couples with young children, whose relationships may have already been under pressure prior to the pandemic. Reduced couples' satisfaction has been reported since …

Accepts healthy volunteers
York University
 (3.0 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose Ranging Study to Assess the Efficacy, Safety, and Tolerability of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma (TIDE-asthma)

This is a parallel, Phase 2, global, multicenter, randomized, double-blind, placebo-controlled, dose-ranging, four-arms study for treatment. The purpose of this study is to assess the efficacy, safety, and tolerability of add-on therapy with amlitelimab in adult participants with moderate-to-severe asthma. Study details include: The study duration (per participant) will be …

Investigational Site Number :1240005
 (10.1 away) Contact site
  • 0 views
  • 13 Oct, 2022
  • +5 other locations
A Randomized Phase II Double-Blind Placebo-Controlled Trial of Acetylsalicylic Acid (ASA) in Prevention of Ovarian Cancer in Women With BRCA 1/2 Mutations (STICs and STONEs)

While ASA is not a cancer medication, research suggests that taking ASA reduces the probability of getting many types of cancer because of its anti-inflammatory action. Inflammation in the ovaries during ovulation is thought to contribute to the development of ovarian cancer, and, because ASA is an anti-inflammatory medication, it …

Accepts healthy volunteers
North York General Hospital
 (5.5 away) Contact site
  • 809 views
  • 27 Oct, 2022
  • +16 other locations
Laser Vaginal Treatment for GSM

Genitourinary Syndrome of Menopause (GSM) due to low estrogen levels affects about half of post-menopausal women and may have a dramatic impact on women's quality of life. Women complain of vaginal dryness, itching, discomfort, malodour, painful intercourse and may have urinary urgency, irritation, bladder/urethral pain and recurring bladder infections. First-line …

Accepts healthy volunteers
Sunnybrook Health Sciences Centre, University of Toronto
 (7.2 away) Contact site
  • 68 views
  • 27 Oct, 2022
  • 1 location
Laser Vaginal Treatment for Stress Urinary Incontinence

RCT designed to answer the question: Does the application of Erbium: YAG laser treatment to the vagina improve urine control for women with SUI?

prolapse
cough
Accepts healthy volunteers
incontinence
leakage of urine
Sunnybrook Health Sciences Centre, University of Toronto
 (7.2 away) Contact site
  • 27 views
  • 27 Oct, 2022
  • 1 location