Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

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Found 180 clinical trials
A Phase 2 Study of Quantitative Ultrasound to Guide Adaptive Chemotherapy Among Women With Breast Cancer

The primary objective of this study is to assess the feasibility of randomizing breast cancer patients to quantitative ultrasound to guide adaptive Neoadjuvant Chemotherapy as compared to standard clinical monitoring and therapy. The Investigators have previously demonstrated that high-frequency ultrasound and spectroscopy, and recently conventional-frequency ultrasound and spectroscopy may be …

Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 21 Oct, 2022
  • 1 location
A Randomized Phase III Trial of Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer [PLATON] (PLATON)

The purpose of this study is to compare the effects of ablative therapy (radiation or surgery) to all sites of disease combined with standard treatments on prostate cancer, compared to the standard or usual treatments used to treat this disease.

metastasis
adenocarcinoma
adenocarcinoma of prostate
bone scan
cfdna
Odette Cancer Centre
 (7.2 away) Contact site
  • 71 views
  • 21 Oct, 2022
  • +14 other locations
A Phase 2b, Randomized, Double-Mask, Placebo-Controlled, Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) (LIDS)

The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twice daily (BID) vs. placebo, at 24 weeks in the treatment of subjects with active, moderate to severe thyroid eye disease (TED).

Toronto Retina Institute
 (7.5 away) Contact site
  • 0 views
  • 22 Oct, 2022
  • +8 other locations
A Randomized, Controlled, Split Face Study of a 1726 nm Laser for the Treatment of Acne Vulgaris

The purpose of this study is to evaluate the onset, duration, efficacy and safety of the laser for the treatment of acne vulgaris.

Canadian Dermatology Centre
 (6.9 away) Contact site
  • 0 views
  • 23 Oct, 2022
  • +1 other locations
Percutaneous MitraClip Device or Surgical Mitral Valve REpair in PAtients With PrImaRy MItral Regurgitation Who Are Candidates for Surgery (REPAIR MR)

The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of MitraClip™ device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve has been determined to be suitable for correction by MV repair surgery by the …

mitral valve repair
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 7 views
  • 11 Oct, 2022
  • +53 other locations
Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome Phase IV Pilot Study (TILE)

The TILE pilot study will be a multicenter, open-label, assessor-blinded RCT (randomized control trial) comparing extended LMWH (Low Molecular Weight Heparin) vs. DOAC (Direct Oral Anticoagulants) to PTS (prevent post thrombotic syndrome) in patients with DVT (Deep Vein Thrombosis).

tinzaparin
blood clot
post thrombotic syndrome
rivaroxaban
heparin
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 12 Oct, 2022
  • +3 other locations
Treatment to Promote Self-regulation in Children With Autism Spectrum Disorder

This study will evaluate the feasibility of repetitive Transcranial Magnetic Stimulation (rTMS) in Autism Spectrum Disorder (ASD) with self-regulation impairment. Baseline and follow-up participant visits will include behavioral assessments of self-regulation and magnetic resonance imaging (MRI) to determine neurophysiological outcomes before and after rTMS treatment.

Bloorivew Research Institute
 (7.5 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
Lausanne Trialogue Paradigm - Brief: A Family Model for Child Mental Health in a Community Setting (LTP-B)

The current study is a feasibility pilot of the Lausanne Trialogue Play paradigm Intervention Brief (LTP-Brief), a family systems therapy implemented in a community mental health setting. We will study the ultrabrief, virtual therapy to assess the feasibility of a future pilot RCT. Feasibility metrics include resource, scientific, and management …

Accepts healthy volunteers
York University
 (3.0 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA Nephropathy

The purpose of this study is to evaluate the effectiveness and safety of IONIS-FB-LRx, an antisense inhibitor of complement factor B messenger ribonucleic acid (CFB mRNA), and to evaluate the effect of IONIS-FB-LRx on plasma factor B (FB) levels and serum AH50, CH50 activity in participants with primary immunoglobulin A …

IONIS Investigative Site
 (7.4 away) Contact site
  • 16 views
  • 04 Oct, 2022
  • +5 other locations
Dairy and Inflammation Study (DRIVE)

The purpose of this study is to determine whether 6-weeks of increased dairy consumption can reduce inflammation and other markers of chronic disease while fasted or following a high-fat meal.

body mass index
fasting
York University
 (3.0 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location