Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

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Found 405 clinical trials
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Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.

stimulant
sodium oxybate
cataplexy
multiple sleep latency test
sleep disorder
Somni Research Inc
 (5.5 away) Contact site
  • 0 views
  • 10 Jul, 2018
  • +52 other locations
featured
C2541013 MIRNA NASH  

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

Toronto Liver Centre
 (9.0 away)
  • 261 views
  • 19 Jul, 2021
  • +64 other locations
featured
INCB 18424-303: Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 1 (TRuE-AD1)

A Phase 3, randomized (2:2:1), double-blind, 8-week vehicle control efficacy and safety study of ruxolitinib followed by a randomized, double-blind, 44-week long term safety (LTS) extension period.  In the LTS period,  participants initially randomized to vehicle will receive either ruxolitinib 0.75% or 1.5% cream.  All participants will have follow-up assessments …

atopic dermatitis
eczema
atopic dermatitis/eczema
YORK DERMATOLOGY CENTER
 (4.2 away) Contact site
  • 242 views
  • 14 Dec, 2020
  • +37 other locations
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A Phase 2, Randomized, Dose-Ranging, Vehicle-Controlled and Triamcinolone 0.1% Cream–Controlled Study to Evaluate the Safety and Efficacy of INCB018424 Phosphate Cream Applied Topically to Adults With Atopic Dermatitis

A Phase 2, Randomized, Dose-Ranging, Vehicle-Controlled and Triamcinolone 0.1% Cream–Controlled Study to Evaluate the Safety and Efficacy of INCB018424 Phosphate Cream Applied Topically to Adults With Atopic Dermatitis

dermatitis
atopic dermatitis
atopic dermatitis/eczema
YORK DERMATOLOGY CENTER
 (4.2 away) Contact site
  • 1344 views
  • 08 Dec, 2020
  • +52 other locations
High Blood Pressure Strategy (HBPS)

This program developed by the HSFO aims at helping people of Ontario and their primary healthcare providers better diagnose, manage and control high blood pressure. The High Blood Pressure Strategy brings together healthcare providers and patients to improve the way in which family doctors, nurse practitioners and pharmacists work together …

essential hypertension
raised blood pressure
Heart and Stroke Foundation of Ontario
 (7.5 away) Contact site
  • 29 views
  • 07 Nov, 2020
  • 1 location
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

cyclin d1
acalabrutinib
bendamustine
rituximab
Research Site
 (7.2 away) Contact site
  • 1270 views
  • 21 Jul, 2021
  • +250 other locations
A Study of Rucaparib Versus Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib versus treatment with physician's choice of abiraterone acetate, enzalutamide, or docetaxel.

Sunnybrook Odette Cancer Centre
 (7.2 away) Contact site
  • 2496 views
  • 22 Jul, 2021
  • +209 other locations
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

testosterone
ct scan
gonadotropin releasing hormone
abiraterone
androgen
Research Site
 (7.2 away) Contact site
  • 200 views
  • 23 Jul, 2021
  • +194 other locations
Long-term Safety Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have participated in a Novartis ofatumumab clinical MS study. Vaccination sub-study The purpose of this research sub-study is to find out the effects of ofatumumab on the development of antibody …

tetanus
ofatumumab
pneumococcal conjugate vaccine
Novartis Investigative Site
 (7.2 away) Contact site
  • 234 views
  • 16 May, 2021
  • +260 other locations
A Study of Biomarker-Directed Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)

This study will investigate the utility of biomarker-based triage for study participants with advanced non-small cell lung cancer (NSCLC) without prior systemic therapy. Study participants within groups defined by a biomarker-based classifier (gene expression profile [GEP] and tumor mutational burden [TMB]) will be randomized to receive pembrolizumab in combination with …

Sunnybrook Health Science Centre ( Site 0304)
 (7.2 away) Contact site
  • 352 views
  • 21 Jul, 2021
  • +92 other locations