Sudbury, Canada Clinical Trials

A listing of Sudbury, Canada clinical trials actively recruiting patients volunteers.

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Found 66 clinical trials
Duration of Anti-PD-1 Therapy in Metastatic Melanoma (STOP-GAP)

The purpose of this study is to compare the effects on patients with metastatic melanoma of taking a government approved and paid-for PD-1 inhibitor intermittently, with taking the same type of agent continuously. Researchers want to see if the two ways of giving this type of treatment work equally well …

Health Sciences North
 (4.2 away) Contact site
  • 384 views
  • 24 Mar, 2022
  • +28 other locations
A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864) in Addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

serous adenocarcinoma
serum pregnancy test
step 2
measurable disease
cancer
Health Sciences North
 (4.2 away) Contact site
  • 198 views
  • 16 Sep, 2022
  • +184 other locations
A Phase III, Open-Label, Randomized Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Patients With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer Who Have Not Progressed After Concurrent Platinum-Based Chemoradiation (SKYSCRAPER-03)

The purpose of this study is to evaluate the efficacy and safety of atezolizumab in combination with tiragolumab compared with durvalumab in participants with locally advanced, unresectable Stage III non-small cell lung cancer (NSCLC) who have received at least two cycles of concurrent platinum-based chemoradiotherapy (CRT) and have not had …

lung carcinoma
chemoradiotherapy
cancer chemotherapy
durvalumab
stage iii non-small cell lung cancer
Health Sciences North
 (4.2 away) Contact site
  • 0 views
  • 18 Sep, 2022
  • +175 other locations
Randomized Trial of Hypofractionated LocoRegional Radiotherapy in Breast Cancer and Lymphedema (RHEAL) (RHEAL)

The primary objective is to determine if hypofractionated radiotherapy (RT) delivered over 1 week to the breast and regional nodes (supraclavicular, axillary and internal mammary) following breast conserving surgery (BCS), or to the chest wall and regional nodes following mastectomy, is non-inferior to conventional fractionation delivered over 3 weeks in …

breast cancer
breast-conserving surgery
invasive carcinoma
carcinoma
cancer
Northeast Cancer Centre, Health Sciences North
 (4.2 away) Contact site
  • 0 views
  • 18 Sep, 2022
  • +13 other locations
A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN) (KUNLUN)

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study to assess the efficacy and safety of durvalumab administered concurrently with dCRT in patients with locally advanced, unresectable esophageal squamous cell carcinoma (ESCC).

durvalumab
carcinoma
fluorouracil
capecitabine
squamous cell carcinoma
Research Site
 (157.8 away) Contact site
  • 4 views
  • 20 Sep, 2022
  • +91 other locations
The Effect of Tirzepatide Versus Dulaglutide on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes (SURPASS-CVOT) (SURPASS-CVOT)

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
hemoglobin a1c
body mass index
Janik Research Corporation
 (2.9 away) Contact site
  • 951 views
  • 22 Sep, 2022
  • +583 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer (TAILOR RT)

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

tamoxifen
breast-conserving surgery
metastasis
HER2
mastectomy
Health Sciences North
 (4.2 away) Contact site
  • 768 views
  • 04 Oct, 2022
  • +325 other locations
Stereotactic Ablative Radiotherapy for Comprehensive Treatment of 4-10 Oligometastatic Tumors (SABR-COMET 10)

In patients with a limited oligometastatic burden (cancer has spread but is not yet considered metastatic), emerging evidence suggests that treatment of all sites of disease with ablative therapies can improve patient outcomes, including overall- and progression-free survival. The application of Stereotactic Ablative Radiotherapy (SABR) for patients with 4-10 metastatic …

cancer
stereotactic body radiation therapy
metastasis
primary tumor
Health Sciences North
 (4.2 away) Contact site
  • 42 views
  • 04 Oct, 2022
  • +12 other locations
Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis (SAFE-D)

The prevention of atrial fibrillation related thromboembolism in the dialysis population is unclear. While the practice of anticoagulation appears favorable in patients with mild-to-moderate chronic kidney disease, no patients with severe chronic kidney disease (estimated glomerular filtration rate <25 ml/min), and specifically those receiving dialysis, have been included in randomized …

heart failure
embolism
renal disease
thromboembolism
chronic kidney disease
Health Sciences North
 (4.2 away) Contact site
  • 6 views
  • 15 Jul, 2022
  • +27 other locations
A Randomized Phase III Trial of Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer [PLATON] (PLATON)

The purpose of this study is to compare the effects of ablative therapy (radiation or surgery) to all sites of disease combined with standard treatments on prostate cancer, compared to the standard or usual treatments used to treat this disease.

bone scan
metastasis
cfdna
adenocarcinoma of prostate
adenocarcinoma
Health Sciences North
 (4.2 away) Contact site
  • 71 views
  • 16 Sep, 2022
  • +13 other locations