St. John, Canada Clinical Trials

A listing of St. John, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 28 clinical trials
featured
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

squamous non-small cell lung cancer
lung carcinoma
experimental drug
cancer
platinum-based chemotherapy
Saint John Regional Hospital
 (2.1 away) Contact site
  • 199 views
  • 28 Jun, 2021
  • +182 other locations
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

Research site
 (1.2 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +193 other locations
Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC)

This is a Phase III, randomized, parallel-arm, placebo controlled, double blind, multicenter study assessing the efficacy and safety of durvalumab versus placebo following SoC chemotherapy in patients with completely resected stage II-III NSCLC who are MRD+ post surgery

lung carcinoma
cancer chemotherapy
durvalumab
Research Site
 (1.2 away) Contact site
  • 102 views
  • 25 Jul, 2021
  • +245 other locations
Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy.

This is a Phase III double-blind, placebo-controlled study of Durvalumab versus Placebo in patients with stage II-III NSCLC who are MRD-positive following curative intent therapy.

lung carcinoma
durvalumab
Research site
 (1.2 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +186 other locations
Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS) Chronic Myelomonocytic Leukemia (CMML) or Low-Blast Acute Myelogenous Leukemia (AML)

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared with single-agent azacitidine. (An event is defined as death or transformation to AML in participants with MDS or CMML, whichever occurs first, and is defined as death in participants …

chronic myelomonocytic leukemia
myelodysplastic syndromes
induction chemotherapy
myeloid leukemia
myelomonocytic leukemia
Saint John Regional Hospital
 (1.2 away) Contact site
  • 341 views
  • 24 Jul, 2021
  • +319 other locations
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for …

x-rays
fatigue
cancer
exercise intervention
fatigue assessment and management
Regional Health Authority B, Zone 2
 (1.2 away) Contact site
  • 397 views
  • 23 Jul, 2021
  • +50 other locations
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack in the prior 5 years, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.

stemi
coronary artery bypass graft
ace inhibitor
revascularisation
beta blockers
New Brunswick Heart Centre
 (0.3 away) Contact site
  • 258 views
  • 21 Jan, 2021
  • +82 other locations
Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial

Patients who are critically ill in the in the Intensive Care Unit (ICU), especially those who need a breathing machine, can develop ulcers in the stomach that bleed. To prevent bleeding, many such patients around the world receive a drug called pantoprazole that decreases acid production. However, today, compared to …

resuscitation
Saint John Regional Hospital
 (1.2 away) Contact site
  • 285 views
  • 24 Jan, 2021
  • +35 other locations
Remote Patient Management of CIEDs

This is a Canadian multicenter randomized controlled trial to assess remote patient management. Patients will be randomized to remote patient management versus usual care, and will be stratified by RemoteView vs no RemoteView utilization, as well as by center.

Saint John Regional Hospital
 (1.2 away) Contact site
  • 5 views
  • 18 Apr, 2021
  • +8 other locations
Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

The ascending aorta conducts blood from the heart to the rest of the body. The ascending aorta can become enlarged, and the risk of tearing and rupturing becomes higher with larger aorta. When the ascending aorta tears or ruptures, the risk dying is high even if surgery is done as …

Horizon Health Network
 (1.3 away) Contact site
  • 68 views
  • 29 Jun, 2021
  • +20 other locations