St. John's, Canada Clinical Trials

A listing of St. John's, Canada clinical trials actively recruiting patients volunteers.

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Found 92 clinical trials
Savonix Inc-Alzheimer’s Disease Discovery

This study is looking for adults over the age of 22. This is an online cognitive study.Click the link below for more information:https://www.assiststudy.org/

Accepts healthy volunteers
Online studies
Online Study Center
(online study) Contact site
  • 630 views
  • 23 Sep, 2022
  • 1 location
  • Online study
Objective, Passive Assessment of LRRK2 Carriers (OPAL)

This study is currently only open to active participants in the University of Rochester’s VALOR-PD study. The goal of this project is to identify objective, sensitive, and convenient measures for assessing early signs of Parkinson's disease in an at-risk population at home. We will do so by using a wireless …

movement disorder
Online studies
University of Rochester
(online study) Contact site
  • 64 views
  • 12 May, 2022
  • 1 location
  • Online study
A Phase 4, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease (STAR)

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) axial disease by assessing reduction in axial symptoms and inflammation.

spondylitis
biological drug
psoriatic plaque
apremilast
NSAID
Eastern Regional Health Authority, St. Clare's Mercy Hospital
 (0.4 away) Contact site
  • 107 views
  • 18 Sep, 2022
  • +97 other locations
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SPR001 (Tildacerfont) in Reducing Supraphysiologic Glucocorticoid Use in Adult Subjects With Classic Congenital Adrenal Hyperplasia

An investigation of the ability of Tildacerfont to reduce supraphysiologic glucocorticoid dosing in classic CAH subjects up to 76 weeks of treatment. Optional open label extension up to 240 weeks.

prednisolone
deficiency
21-ohd
prednisone
Spruce Study Site
 (916.7 away) Contact site
  • 10 views
  • 19 Sep, 2022
  • +52 other locations
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase III Study With a Long-Term, Open-Label Extension to Evaluate the Efficacy and Safety of TRM-201 (Rofecoxib) in Patients With Hemophilic Arthropathy (RESET-HA)

This is a multicenter, randomized, double-blind study to evaluate the efficacy and safety of TRM-201 (rofecoxib) versus Placebo in the treatment of patients with hemophilic arthropathy (HA) over a 12-week period (Part I) that is followed by a year-long (52 week) open-label extension (Part II) to further evaluate the safety …

Hamilton Health Sciences Centre
 (1338.0 away) Contact site
  • 1 views
  • 22 Sep, 2022
  • +17 other locations
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of SPR001 (Tildacerfont) in Adult Subjects With Classic Congenital Adrenal Hyperplasia

An investigation of the efficacy and safety of up to 70 weeks of treatment with Tildacerfont in subjects with classic CAH who have elevated biomarkers at baseline on their current GC regimen. Optional open label treatment extension period up to 240 weeks with 200mg tildacerfont QD.

17-hydroxyprogesterone
prednisolone
deficiency
21-ohd
prednisone
Spruce Study Site
 (916.7 away) Contact site
  • 28 views
  • 22 Sep, 2022
  • +53 other locations
Re-Irradiation of Progressive or Recurrent DIPG

This is a single-arm, non-randomized study of re-irradiation of diffuse intrinsic pontine glioma (DIPG)

Janeway Child Health Centre
 (1.6 away) Contact site
  • 8 views
  • 24 Mar, 2022
  • +17 other locations
A Phase 3 Clinical Trial to Evaluate Efficacy and Safety of Twice-daily Applications of Delgocitinib Cream 20 mg/g Compared With Cream Vehicle for a 16-week Treatment Period in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema (DELTA TEEN)

The purpose of this trial is to test if delgocitinib cream is effective at treating chronic hand eczema (CHE) and what side effects it may have, in children aged 12-17. There will be a range of assessments that rate the severity and extent of CHE symptoms, general health and quality …

LEO Pharma investigational site
 (1.8 away) Contact site
  • 0 views
  • 19 Sep, 2022
  • +4 other locations
An Exploratory, Open-Label, Oligo-Center Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravenous DNV3837 in Subjects With Clostridium Difficile Infection

This is an open-label study to evaluate the safety, efficacy, and PK of DNV3837 at a dose of 1.5 mg/kg actual body weight(BW)/day administered via IV infusion in subjects with CDI. The study will be conducted in 2 subsequent parts. In Part 1 of the study, 10 subjects of either …

Health Sciences Center, Eastern Health
 (1.5 away) Contact site
  • 29 views
  • 20 Sep, 2022
  • +5 other locations
Preventing Arthritis in a Multi-Center Psoriasis At-Risk Cohort (PAMPA)

This is a multi-center (North-America), randomized, double-blind, placebo-controlled, wait-list, interventional, preventive trial of guselkumab in high-risk psoriasis patients compared to non-biologic standard of care. The primary objective of our proposed trial will be to test the hypothesis that a prolonged, unresolved skin inflammation coupled with musculoskeletal power-doppler ultrasound (MSKPDUS) abnormalities …

guselkumab
Memorial University
 (0.4 away) Contact site
  • 0 views
  • 20 Sep, 2022
  • +2 other locations