St John's, Canada Clinical Trials

A listing of St John's, Canada clinical trials actively recruiting patients volunteers.

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Found 24 clinical trials
A Study to Assess the Efficacy Safety and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP)

The purpose of this study is to demonstrate the clinical efficacy of rozanolixizumab in maintenance treatment and assess safety and tolerability of rozanolixizumab in adult study participants with primary immune thrombocytopenia (ITP).

Tp0006 50384
 (1130.5 away) Contact site
  • 15 views
  • 11 Jul, 2021
  • +49 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site 8000
 (0.5 away) Contact site
  • 21 views
  • 16 Jul, 2021
  • +470 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

plaque psoriasis
apremilast
risankizumab
arthritis
systemic therapy
Karma Clinical Trials /ID# 230339
 (3.5 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +61 other locations
Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis

The main purpose of the study is to assess the efficacy and safety of nemolizumab after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with topical treatments.

Galderma Investigational Site
 (0.5 away) Contact site
  • 95 views
  • 16 Jul, 2021
  • +458 other locations
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis

This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia (platelet count <50,000/L). Approximately 348 patients in total will be enrolled, randomized 2:1 to either pacritinib (approximately 232 patients) or …

neutrophil count
thrombocythemia
left upper quadrant pain
conjugated bilirubin
thrombocytosis
Eastern Regional Health Authority
 (1.6 away) Contact site
  • 506 views
  • 19 Jul, 2021
  • +177 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

bypass graft
cardiac resynchronization therapy
iron
ejection fraction
nt-probnp
Health Sciences Centre
 (1.6 away) Contact site
  • 5316 views
  • 22 Jul, 2021
  • +365 other locations
Efficacy and Safety Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis

This is a Phase 3, multicenter, randomized, placebo-controlled, double-blind study of the efficacy and safety of apremilast (CC-10004) in pediatric subjects with moderate to severe plaque psoriasis. At least 230 pediatric subjects (ages 6 through 17 years) will be randomized 2:1 to receive either apremilast or placebo for the first …

apremilast
plaque psoriasis
phototherapy
topical agents
systemic therapy
Karma Clinical Trials
 (3.5 away) Contact site
  • 98 views
  • 24 Jul, 2021
  • +284 other locations
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

This study will test how well a new medicine called concizumab works in the body of people with haemophilia A or B without inhibitors. The purpose is to show that concizumab can prevent bleeds in the body and is safe to use. Participants who usually only take medicine to treat …

Novo Nordisk Investigational Site
 (1.6 away) Contact site
  • 36 views
  • 25 Jul, 2021
  • +104 other locations
A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

bimekizumab
antibiotics
hidradenitis
abscess
Hs0004 50159
 (924.1 away) Contact site
  • 339 views
  • 23 Jul, 2021
  • +100 other locations
A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB Subtype DLBCL (ACE-LY-312)

Phase 3 randomized, double-blind, placebo-controlled, study assessing the efficacy and safety of acalabrutinib plus rituximab,cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) vs placebo plus R-CHOP in subjects 65 years of age with previously untreated non-germinal center diffuse large B-cell lymphoma.

Research Site
 (866.5 away) Contact site
  • 0 views
  • 11 Jul, 2021
  • +217 other locations