Scarborough, Canada Clinical Trials

A listing of Scarborough, Canada clinical trials actively recruiting patients volunteers.

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Found 102 clinical trials
A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to see if the study drug mirikizumab is safe and effective in participants with moderately to severely active Crohn's disease.

crohn's disease
ustekinumab
Digestive Health Clinic
 (9.4 away) Contact site
  • 652 views
  • 26 Sep, 2021
  • +1004 other locations
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the …

Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 7 views
  • 15 Sep, 2021
  • +38 other locations
Assessing the Impact of Lipoprotein (a) Lowering With TQJ230 on Major Cardiovascular Events in Patients With CVD

This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)

Novartis Investigative Site
 (8.1 away) Contact site
  • 151 views
  • 23 Sep, 2021
  • +578 other locations
A Phase 2b Diabetic Kidney Disease Study

A Phase 2b Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of MEDI3506 in Subjects with Diabetic Kidney Disease

diabetic nephropathy
nephropathy
Research Site
 (8.3 away) Contact site
  • 54 views
  • 26 Sep, 2021
  • +115 other locations
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

During end-stage kidney disease, clinical guidelines suggest reducing elevated phosphate levels in the blood. However, the effect of lowering blood phosphate levels on important patient-centred outcomes has never been tested. This trial will evaluate whether compared to high levels, lowering blood phosphate levels would reduce death or major events due …

heart disease
renal disease
blood phosphate
diabetes
nephropathy
Scarborough Hospital Network
 (1.5 away) Contact site
  • 91 views
  • 23 Sep, 2021
  • +56 other locations
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

thromboembolism
rivaroxaban
coronary artery bypass graft
vitamin k
anticoagulants
Sunnybrook Hospital
 (8.1 away) Contact site
  • 112 views
  • 23 Sep, 2021
  • +79 other locations
Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

This trial is being done to find out whether tisotumab vedotin works better than chemotherapy to treat cervical cancer. People in this study have cervical cancer that has spread to other parts of the body (metastatic) or has come back after being treated (recurrent). Participants in this trial will be …

gemcitabine
pemetrexed
pembrolizumab
paclitaxel
bevacizumab
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 27 Sep, 2021
  • +40 other locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at …

tumor necrosis factor
vedolizumab
immunomodulators
ustekinumab
corticosteroids
Toronto Immune Digestive Health Institute, Inc
 (9.0 away) Contact site
  • 12 views
  • 26 Sep, 2021
  • +555 other locations
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome (MDS) is a group of disorders that gradually affect the ability of a person's bone marrow (semi-liquid tissue present in many bones like backbones) to produce normal blood cells. Some people with MDS have a risk of the disease progressing to acute myeloid leukemia (AML), and a risk …

myeloid leukemia
leukemia
remission
azacitidine
anemia
Sunnybrook Health Sciences Ctr /ID# 219103
 (8.1 away) Contact site
  • 27 views
  • 26 Sep, 2021
  • +343 other locations
Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

The purpose of this study is to determine the efficacy and safety of multiple CSJ117 doses (0.5; 1; 2; 4 and 8 mg) inhaled once daily compared with placebo, when added to standard-of-care (SoC) asthma therapy in adult patients with uncontrolled asthma with respect to change from baseline in FEV1 …

corticosteroids
Novartis Investigative Site
 (8.1 away) Contact site
  • 48 views
  • 22 Sep, 2021
  • +143 other locations