Scarborough, Canada Clinical Trials

A listing of Scarborough, Canada clinical trials actively recruiting patients volunteers.

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Found 102 clinical trials
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

The purpose of this study is to determine the safety and efficacy of combination therapy with pembrolizumab (MK-3475) and lenvatinib (E7080/MK-7902) in participants with triple negative breast cancer (TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic cancer.

combined modality therapy
lenvatinib
extrahepatic cholangiocarcinoma
carcinoma
epidermal growth factor
Sunnybrook Research Institute ( Site 0207)
 (8.1 away) Contact site
  • 611 views
  • 26 Sep, 2021
  • +92 other locations
This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia

This is a study in adults with schizophrenia. The study tests whether a medicine called BI 425809 together with brain training improves mental abilities. Participants take study medication once a day for 12 weeks. At the start of the study, the participants are put into 2 groups. It is decided …

clozapine
cognitive training
anticholinergics
antidepressants
antipsychotics
Centre for Addiction and Mental Health (CAMH)
 (8.3 away) Contact site
  • 774 views
  • 18 Sep, 2021
  • +59 other locations
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

This study is designed to determine the efficacy and safety of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple negative breast cancer

antineoplastic
triple negative breast cancer
erbb2
breast cancer
paclitaxel
Research Site
 (8.1 away) Contact site
  • 400 views
  • 27 Sep, 2021
  • +64 other locations
Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata

The overall objectives of the study are to evaluate long-term safety of CTP-543 and to assess long-term effects of CTP-543 on treating hair loss in adult patients with chronic, moderate to severe alopecia areata.

areata alopecia
alopecia
Lynderm Research Inc.
 (6.9 away) Contact site
  • 491 views
  • 25 Sep, 2021
  • +47 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

overweight or obesity
cardiovascular disease
body mass index
Novo Nordisk Investigational Site
 (2.4 away) Contact site
  • 7800 views
  • 25 Sep, 2021
  • +1166 other locations
Efficacy and Safety Study of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in ESA Na ve Subjects Who Require Red Blood Cell Transfusions

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept (ACE-536) …

erythropoietin
blood transfusion
bone marrow procedure
cancer
anemia
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 294 views
  • 27 Sep, 2021
  • +293 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

mirikizumab
endoscopy
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 386 views
  • 27 Sep, 2021
  • +913 other locations
A Phase 3 Efficacy Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer

A study of zolbetuximab (IMAB362) plus mFOLFOX6 versus placebo plus mFOLFOX6 in subjects with Claudin 18.2 positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical study for adult patients who have any of: advanced unresectable gastric …

Site CA15011
 (8.1 away) Contact site
  • 486 views
  • 16 Sep, 2021
  • +239 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

axillary lymph node dissection
invasive carcinoma
carcinoma
erbb2
metastasis
Odette Cancer Centre- Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 598 views
  • 23 Sep, 2021
  • +323 other locations
Long-Term PF-06651600 for the Treatment of Alopecia Areata

This is a global Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called PF-06651600) in adults and adolescents (12 years and older) who have alopecia areata. Eligible patients from the prior studies B7931005 (NCT02974868) and B7981015 (NCT03732807) will have an opportunity to enroll as …

alopecia
androgenic alopecia
alopecia totalis
areata alopecia
alopecia universalis
Lynderm Research Inc.
 (6.9 away) Contact site
  • 1585 views
  • 25 Sep, 2021
  • +177 other locations