Saskatoon, Canada Clinical Trials

A listing of Saskatoon, Canada clinical trials actively recruiting patients volunteers.

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Found 23 clinical trials
Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Sometimes, cancer patients receive an initial treatment, followed by additional treatment to lower the chance of cancer coming back. The standard or usual treatment for this type of disease is initially having radiation therapy at the same time as chemotherapy (with a drug called cisplatin), with no additional therapy afterwards

pet/ct scan
x-rays
neutrophil count
human papillomavirus
cancer
Saskatoon Cancer Centre
 (1.2 away) Contact site
  • 56 views
  • 21 Jul, 2021
  • +29 other locations
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Phase III, double-blind, randomised study assessing the efficacy of capivasertib + fulvestrant vs placebo + fulvestrant for the treatment of patients with locally advanced (inoperable) or metastatic HR+/HER2- breast cancer following recurrence or progression on or after AI therapy.

Research Site
 (1.2 away) Contact site
  • 50 views
  • 11 Jul, 2021
  • +223 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

antirheumatics
rheumatism
stiffness
methotrexate
Dr. Latha Naik /ID# 227823
 (0.7 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +291 other locations
A Clinical Trial of COVAC-2 in Healthy Adults

VIDO has developed a vaccine called COVAC-2. The study vaccine contains a portion of the SARS-CoV-2 spike protein, called S1. The spike protein is the part of the virus that is responsible for attaching to the surface of host cells. COVAC-2 contains a SWE adjuvant. An adjuvant is a compound …

Canadian Center for Vaccinology, Dalhousie University
 (2002.4 away) Contact site
  • 0 views
  • 14 Jul, 2021
  • +1 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

ejection fraction
bypass graft
cardiac resynchronization therapy
b-type natriuretic peptide
iron
Royal University Hospital
 (1.1 away) Contact site
  • 5316 views
  • 22 Jul, 2021
  • +365 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

endoscopy
mirikizumab
Royal University Hospital
 (1.1 away) Contact site
  • 386 views
  • 21 Jul, 2021
  • +906 other locations
A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis

This study consists of two periods. The objective of Period 1 is to evaluate the efficacy of upadacitinib in combination with a 26-week corticosteroid (CS) taper regimen compared to placebo in combination with a 52-week CS taper regimen, as measured by the proportion of participants in sustained remission at Week …

Polmed Research Inc /ID# 201843
 (0.2 away) Contact site
  • 311 views
  • 15 Jul, 2021
  • +290 other locations
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer

The purpose of this study is to evaluate the effectiveness of niraparib in combination with abiraterone acetate plus prednisone (AAP) compared to AAP and placebo.

Saskatoon Cancer Centre
 (1.2 away) Contact site
  • 498 views
  • 10 Jul, 2021
  • +487 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

stemi
acute coronary syndrome
myocardial infarction
stroke
arterial disease
1240095 - Royal University Hospital
 (1.1 away) Contact site
  • 1118 views
  • 21 Jul, 2021
  • +3430 other locations
An Induction Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)

The purpose of this study is to evaluate the safety and efficacy of Mirikizumab in participants with moderately to severely active ulcerative colitis (UC) who have had an inadequate response to, loss of response, or intolerant to conventional or biologic therapy for UC.

mirikizumab
Royal University Hospital
 (1.1 away) Contact site
  • 1722 views
  • 21 Jul, 2021
  • +880 other locations