Sarnia, Canada Clinical Trials

A listing of Sarnia, Canada clinical trials actively recruiting patients volunteers.

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Found 44 clinical trials
Safety Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19

This is a phase 2 study in which subjects with coronavirus disease 2019 (COVID-19) will receive VIR-7831 (Sotrovimab) Generation 1 (Gen1) or VIR-7831 (Sotrovimab) Generation 2 (Gen2) and will be assessed for safety, tolerability, and pharmacokinetics.

Investigative Site
 (1.0 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +33 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

rifampin
metastatic colorectal adenocarcinoma
lithium
corticosteroids
metastasis
McLaren-Port Huron
 (3.1 away) Contact site
  • 65 views
  • 25 Jul, 2021
  • +978 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

atezolizumab
monoclonal antibody therapy
investigational agent
hysterectomy
hiv viral load
McLaren-Port Huron
 (2.9 away) Contact site
  • 1047 views
  • 25 Jul, 2021
  • +588 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

metastatic disease
gonadotropin releasing hormone
gnrh
antiretroviral
systemic therapy
Huron Medical Center PC
 (3.1 away) Contact site
  • 6087 views
  • 25 Jul, 2021
  • +1018 other locations
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

This randomized phase III trial studies how well combination chemotherapy (vincristine sulfate, dactinomycin, cyclophosphamide alternated with vincristine sulfate and irinotecan hydrochloride or vinorelbine) works compared to combination chemotherapy plus temsirolimus in treating patients with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle), and has an intermediate chance …

platelet count
actinomycin
glomerular filtration rate
cancer
irinotecan
Huron Medical Center PC
 (3.1 away) Contact site
  • 292 views
  • 25 Jul, 2021
  • +290 other locations
Study to Evaluate the Efficacy Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)

This study will assess the efficacy of vibegron compared with placebo in men with overactive bladder (OAB) symptoms on pharmacological therapy for benign prostatic hyperplasia (BPH) as defined by micturition and urgency episodes.

cancer
micturition chart
alpha blocker
nocturia
benign prostatic hypertrophy
Bluewater Clinical Research Group Inc
 (1.0 away) Contact site
  • 959 views
  • 15 Jul, 2021
  • +170 other locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

eosinophil count
cigarette smoke
antibiotics
muscarinic antagonists
corticosteroids
GSK Investigational Site
 (1.0 away) Contact site
  • 379 views
  • 24 Jul, 2021
  • +232 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

McLaren-Port Huron
 (3.1 away) Contact site
  • 85 views
  • 25 Jul, 2021
  • +331 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

atezolizumab
interleukin 2
nivolumab
il-2
systemic therapy
Huron Medical Center PC
 (3.1 away) Contact site
  • 157 views
  • 25 Jul, 2021
  • +675 other locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

This phase II/III trial studies how well a reduced dose of radiation therapy works with nivolumab compared to cisplatin in treating patients with human papillomavirus (HPV)-positive oropharyngeal cancer that is early in its growth and may not have spread to other parts of the body (early-stage), and is not associated …

neck dissection
fine needle aspiration
chemotherapy drugs
metastasis
primary tumor
McLaren-Port Huron
 (3.1 away) Contact site
  • 16 views
  • 25 Jul, 2021
  • +225 other locations