Sainte Foy, Canada Clinical Trials

A listing of Sainte Foy, Canada clinical trials actively recruiting patients volunteers.

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Found 123 clinical trials
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

apixaban
clopidogrel
antiplatelet therapy
thromboembolism
anticoagulants
H pital Laval
 (0.7 away) Contact site
  • 112 views
  • 15 Sep, 2021
  • +79 other locations
Tezepelumab COPD Exacerbation Study

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 2a Study to Explore the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

ct scan
bronchodilator
severe chronic obstructive pulmonary disease
copd exacerbation
Research Site
 (8.2 away) Contact site
  • 130 views
  • 12 Sep, 2021
  • +107 other locations
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who roll-over into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. …

metastasis
pembrolizumab
mk-3475
major surgery
CHU de Quebec-Universite Laval-Hotel Dieu de Quebec ( Site 2805)
 (4.2 away) Contact site
  • 534 views
  • 15 Sep, 2021
  • +274 other locations
A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment

Selexipag is available in many countries for the treatment of pulmonary arterial hypertension (PAH). Due to the similarities between PAH and chronic thromboembolic pulmonary hypertension (CTEPH) and the observed efficacy of other PAH medicines in CTEPH, it is believed that selexipag could benefit to patients with CTEPH. This study aims …

endarterectomy
pulmonary arterial hypertension
selexipag
Institut Universitaire De Cardiologie Et De Pneumologie De Qu bec
 (0.7 away) Contact site
  • 27 views
  • 09 Sep, 2021
  • +288 other locations
Study of First-line Pembrolizumab (MK-3475) With Lenvatinib (MK-7902/E7080) in Urothelial Carcinoma Cisplatin-ineligible Participants Whose Tumors Express Programmed Cell Death-Ligand 1 and in Participants Ineligible for Platinum-containing Chemotherapy (MK-7902-011/E7080-G000-317/ LEAP-011)

The purpose of this study is to evaluate the efficacy and safety of lenvatinib (MK-7902/E7080) in combination with pembrolizumab (MK-3475) in the treatment of cisplatin-ineligible participants with a Programmed Cell Death-Ligand 1 (PD-L1) Combined Positive Score (CPS) 10, or in participants ineligible for any platinum-containing chemotherapy regardless of CPS, with …

cancer
hearing loss
solid tumour
radical cystectomy
carboplatin
CHU de Quebec-Universite Laval-Hotel Dieu de Quebec ( Site 0104)
 (4.2 away) Contact site
  • 72 views
  • 02 Sep, 2021
  • +229 other locations
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

This randomized phase III trial studies how well combination chemotherapy (vincristine sulfate, dactinomycin, cyclophosphamide alternated with vincristine sulfate and irinotecan hydrochloride or vinorelbine) works compared to combination chemotherapy plus temsirolimus in treating patients with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle), and has an intermediate chance …

irinotecan
cancer
actinomycin
alveolar rhabdomyosarcoma
glomerular filtration rate
Centre Hospitalier Universitaire de Quebec
 (1.0 away) Contact site
  • 292 views
  • 15 Sep, 2021
  • +290 other locations
A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study assessing the activity of durvalumab and chemotherapy administered prior to surgery compared with placebo and chemotherapy administered prior to surgery in terms of pathological complete response.

lung carcinoma
carboplatin/paclitaxel
gemcitabine
cancer chemotherapy
paclitaxel
Research Site
 (0.7 away) Contact site
  • 251 views
  • 02 Sep, 2021
  • +320 other locations
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199) With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL

The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.

bendamustine
rituximab
acp-196
venetoclax
chemoimmunotherapy
Research Site
 (4.7 away) Contact site
  • 342 views
  • 16 Sep, 2021
  • +245 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

metastasis
lung cancer
tyrosine
cardiac disease
pembrolizumab
CHA Hopital L'Enfant-Jesus
 (4.7 away) Contact site
  • 213 views
  • 15 Sep, 2021
  • +832 other locations
Stress Hydrocortisone In Pediatric Septic Shock

SHIPSS is a multi-institutional, prospective, controlled, randomized, double-blinded interventional trial that will examine the potential benefits and risks of adjunctive hydrocortisone prescribed for children with fluid and vasoactive-inotropic refractory septic shock. It is hypothesized that adjunctive hydrocortisone will significantly reduce the proportion of children with poor outcomes, defined as death …

antimicrobial agent
continuous infusion
inotropic agent
norepinephrine
Centre hospitalier de l'Universit Laval
 (1.0 away) Contact site
  • 18 views
  • 07 Sep, 2021
  • +66 other locations