Saint John's, Canada Clinical Trials

A listing of Saint John's, Canada clinical trials actively recruiting patients volunteers.

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Found 12 clinical trials
Featured trial
Caregiver-Provided Life Review for Persons with Dementia

This study, Caregiver-Provided Life Review (C-PLR) is created based on Life Review therapy. It is for persons living with early-stage dementia along with mild depressive symptoms who are 65 years or older, community-dwellers or the residents of senior housing, independent or assisted living facilities conducted by their family members (18 …

depression
Online studies
Accepts healthy volunteers
dementia
Online Study Center
(online study) Contact site
  • 566 views
  • 09 Aug, 2022
  • 1 location
  • Online study
Featured trial
Integument-PED study

We are currently recruiting pediatric and adult patients with mild to moderate atopic dermatitis (eczema) for a study that investigates the safety and efficacy of the ARQ-151 cream. 

Nexus Clinical Research
 (3.9 away) Contact site
  • 53 views
  • 17 Aug, 2022
  • +88 other locations
Magrolimab + Azacitidine Versus Azacitidine + Placebo in Untreated Participants With Myelodysplastic Syndrome (MDS) (ENHANCE)

The primary objective of this study is to evaluate the efficacy of magrolimab in combination with azacitidine compared to that of azacitidine plus placebo in previously untreated participants with intermediate/high/very high risk myelodysplastic syndrome (MDS) by Revised International Prognostic Scoring System (IPSS-R) as measured by complete remission (CR) and overall …

remission
high risk myelodysplastic syndrome
azacitidine
QEII Health Sciences Centre
 (555.8 away) Contact site
  • 6 views
  • 11 Aug, 2022
  • +164 other locations
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (FRONTIER-4)

This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult subjects with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis.

body mass index
COPD
pulmonary disease
corticosteroids
spirometry
Research Site
 (866.5 away) Contact site
  • 96 views
  • 09 Aug, 2022
  • +90 other locations
A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in R/R DLBCL (EPCORE™DLBCL-1)

The drug that will be investigated in the study is an antibody, epcoritamab, also known as GEN3013 . Since the safety and tolerability of epcoritamab has already been studied in previous studies in humans, the main purpose of this study is to evaluate efficacy. To evaluate this, half of the …

CHU de Quebec-Universite Laval
 (864.8 away) Contact site
  • 1 views
  • 10 Aug, 2022
  • +232 other locations
A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)

This study will investigate the efficacy, safety, tolerability, and pharmacokinetics of RO7017773 in participants aged 15-45 years who have been diagnosed with ASD with a score of >/=50 on the Wechsler Abreviated Scale of Intelligence (WASI-II).

Janeway Childrens Health; and Rehabilitation Centre
 (1.6 away) Contact site
  • 38 views
  • 11 Aug, 2022
  • +18 other locations
PERC Health Canada COVID-19

Although there are several licensed vaccines for SAR-CoV-2 (COVID-19) in Canada, none of them are approved for use in children under the age of 12, leaving five million children under 12 years unvaccinated. There is a need to find methods of mass rapid point of care testing in unvaccinated populations …

IWK Health Centre
 (555.1 away) Contact site
  • 41 views
  • 08 Aug, 2022
  • +12 other locations
A Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)

This study will evaluate the pharmacokinetics, pharmacodynamics, safety, immunogenicity, and radiological and clinical effects of subcutaneous (SC) administration of ocrelizumab compared with the intravenous (IV) infusion of ocrelizumab in patients with either relapsing multiple sclerosis (RMS) or primary progressive multiple sclerosis (PPMS).

methylprednisolone
corticosteroids
ocrelizumab
disease or disorder
Memorial University of Newfoundland (MUN) - Faculty of Medicine - St. Clare's Mercy Hospital (SCM)
 (1.5 away) Contact site
  • 0 views
  • 20 Aug, 2022
  • +31 other locations
Aveir Dual-Chamber Leadless i2i IDE Study

Prospective, non-randomized, multi-center, international study designed to evaluate the safety and effectiveness of the Aveir™ Dual-Chamber (DR) Leadless Pacemaker system.

HSC, Eastern Health
 (1.6 away) Contact site
  • 0 views
  • 20 Aug, 2022
  • +76 other locations
A Study to Evaluate the Efficacy, Safety, and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO) (CIMcare)

The purpose of the study is to demonstrate the efficacy and safety of certolizumab pegol in the treatment of moderate to severe chronic plaque psoriasis in study participants aged 6 to 11 and 12 to 17 years.

Ps0007 50158
 (964.8 away) Contact site
  • 18 views
  • 09 Aug, 2022
  • +44 other locations