Richmond Hill, Canada Clinical Trials

A listing of Richmond Hill, Canada clinical trials actively recruiting patients volunteers.

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Found 44 clinical trials
Study of WVE-003 in Patients With Huntington's Disease

This is a Phase 1b/2a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, PK, and PD of WVE-003 in adult patients with early-manifest HD who carry the targeted single nucleotide polymorphism (SNP) - SNP3.

Centre For Movement Disorders
 (9.6 away) Contact site
  • 0 views
  • 10 Sep, 2021
  • +5 other locations
A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

The purpose of this study is to assess the efficacy of seltorexant compared with quetiapine extended-release (XR) as adjunctive therapy to an antidepressant drug in treatment response in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective …

psychosis
major depressive disorder
sertraline
structured clinical interview
vortioxetine
Canadian Phase Onward
 (8.2 away) Contact site
  • 148 views
  • 22 Sep, 2021
  • +180 other locations
A Phase 3 Study to Evaluate the Efficacy and Safety of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata (THRIVE-AA1)

This is a multi-center Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called CTP-543) in adults (18 years and older) who have 50% or greater scalp hair loss. The study is placebo-controlled, meaning that some patients entering the study will not receive active study …

areata alopecia
Lynderm Research Inc.
 (8.7 away) Contact site
  • 33 views
  • 19 Sep, 2021
  • +77 other locations
A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease

A phase 2 randomized, double blind, placebo controlled study evaluating the efficacy and safety of AL002 in participants with Early Alzheimer's Disease.

mini-mental state examination
amyloidosis
alzheimer's disease
Toronto Memory Clinic
 (9.6 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +85 other locations
A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to see if the study drug mirikizumab is safe and effective in participants with moderately to severely active Crohn's disease.

crohn's disease
ustekinumab
Digestive Health Clinic
 (3.5 away) Contact site
  • 652 views
  • 23 Sep, 2021
  • +1004 other locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
Toronto Digestive Diseases Ass /ID# 169106
 (9.6 away) Contact site
  • 630 views
  • 23 Sep, 2021
  • +926 other locations
A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

The purpose of the study is to evaluate pharmacokinetic similarity, efficacy, safety and immunogenicity of multiple switches between ustekinumab and ABP 654 compared with continued use of ustekinumab in participants with moderate to severe plaque psoriasis.

purified protein derivative
tuberculosis
ustekinumab
phototherapy
systemic therapy
North York Research Inc. - Dermatology
 (6.8 away) Contact site
  • 5 views
  • 22 Sep, 2021
  • +90 other locations
A Research Study to Compare Two Types of Insulin a New Insulin Insulin Icodec and an Available Insulin Insulin Degludec in People With Type 2 Diabetes Who Have Not Used Insulin Before (ONWARDS 3)

This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin …

Novo Nordisk Investigational Site
 (6.8 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +86 other locations
Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)

The purpose of this study is to assess the safety and efficacy of lenvatinib (MK-7902/E7080) in combination with pembrolizumab (MK-3475) in participants with metastatic colorectal cancer. The study will also compare lenvatinib plus pembrolizumab with the standard of care treatment of regorafenib and TAS-102 (trifluridine and tipiracil hydrochloride). The primary …

North York General Hospital ( Site 0206)
 (8.7 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +84 other locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at …

tumor necrosis factor
vedolizumab
tumor necrosis factor alpha
immunomodulators
maintenance treatment
Toronto Immune Digestive Health Institute, Inc
 (8.5 away) Contact site
  • 12 views
  • 22 Sep, 2021
  • +555 other locations