Pointe Claire, Canada Clinical Trials

A listing of Pointe Claire, Canada clinical trials actively recruiting patients volunteers.

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Found 446 clinical trials
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Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to assess …

McGill University Health Center Research Institute /ID# 222614
 (9.7 away) Contact site
  • 181 views
  • 29 Apr, 2021
  • +224 other locations
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A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

www.MyelofibrosisResearch.com This is a Phase 2 open-label, multicenter study evaluating tolerability and efficacy of navitoclax alone or when added to ruxolitinib in participants with myelofibrosis.

Jewish General Hospital /ID# 217586
 (8.4 away) Contact site
  • 254 views
  • 29 Apr, 2021
  • +134 other locations
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Fox Insight - Online Parkinson's Health and Genetic Study

Fox Insight is an online study gathering health information from tens of thousands of people with and without Parkinson’s disease.  Study participation does not require any travel and all you need is an internet connection to start today at www.foxinsight.org Fox Insight volunteers are invited to take part in virtual …

www.foxinsight.org
 (8.1 away) Contact site
  • 3560 views
  • 29 Mar, 2021
  • +333 other locations
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COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 – Canada  

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements.   This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept …

epoetin alfa
Sir Mortimer B Davis Jewish General Hospital
 (8.4 away)
  • 33 views
  • 03 Aug, 2021
  • +9 other locations
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We are currently recruiting participants for the BLUEPRINT study. This study investigates the effectiveness, safety, and tolerability of the drug BLU-5937 for chronic itch in people with eczema.

The BLUEPRINT study consists of taking two tablets orally, twice a day, for a period of 4 weeks. This treatment is experimental. You will have 50% chance to receive BLU-5937 and 50% chance to receive the placebo. There will be a total of 5 visits at the clinic and 2 …

eczema
atopic dermatitis/eczema
dermatitis
adult atopic dermatitis
atopic dermatitis
Innovaderm Research
 (9.0 away) Contact site
  • 0 views
  • 10 Dec, 2020
  • +24 other locations
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

Hopital du Sacre-Coeur de Montreal
 (5.8 away) Contact site
  • 41 views
  • 26 Jan, 2021
  • +97 other locations
A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced/metastatic Merkel cell carcinoma (MCC).

Sir Mortimer B. Davis Jewish General Hospital
 (8.4 away) Contact site
  • 21 views
  • 26 Jan, 2021
  • +117 other locations
A Study of Biomarker-Directed Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)

This study will investigate the utility of biomarker-based triage for study participants with advanced non-small cell lung cancer (NSCLC) without prior systemic therapy. Study participants within groups defined by a biomarker-based classifier (gene expression profile [GEP] and tumor mutational burden [TMB]) will be randomized to receive pembrolizumab in combination with …

Jewish General Hospital ( Site 0307)
 (8.4 away) Contact site
  • 352 views
  • 02 Aug, 2021
  • +92 other locations
Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)

To evaluate the safety and efficacy of Zimura (complement factor C5 inhibitor) compared to Sham in subjects with autosomal recessive Stargardt disease 1 (STGD1).

Montreal Children's Hospital
 (9.7 away) Contact site
  • 114 views
  • 24 Jul, 2021
  • +40 other locations
A Safety Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

A randomized withdrawal study in which responders to open-label treatment with tofacitinib will be randomized in a 1:1 ratio to tofacitinib or placebo in a double-blind phase. In the double-blind phase "time to sJIA flare" will be evaluated as primary endpoint and subjects will be discontinued once they experience sJIA …

McGill University Health Center, Glen Site
 (9.7 away) Contact site
  • 134 views
  • 02 Aug, 2021
  • +100 other locations