Peterborough, Canada Clinical Trials

A listing of Peterborough, Canada clinical trials actively recruiting patients volunteers.

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Found 36 clinical trials
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on cognitive decline using the Alzheimer's Disease Assessment Scale Cognitive subscale 13-item version (ADAS-Cog13).

cognitive assessment
cognitive decline
dementia
alzheimer's disease
Kawartha Centre - Redefining Healthy Aging
 (0.2 away) Contact site
  • 3 views
  • 07 Sep, 2021
  • +148 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

stroke
arterial disease
infarct
diabetes
myocardial infarction
Research Site
 (0.6 away) Contact site
  • 542 views
  • 22 Sep, 2021
  • +1332 other locations
Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

The purpose of this extension study is to evaluate maintenance of HiSCR response at Week 104 in either continuous or interrupted therapy (using a randomized withdrawal period) of two dose regimens and to assess long-term efficacy, safety and tolerability of secukinumab in subjects with moderate to severe hidradenitis suppurativa completing …

secukinumab
expanded access trial
hidradenitis
Novartis Investigative Site
 (1.9 away) Contact site
  • 45 views
  • 26 Aug, 2021
  • +170 other locations
OLE of Phase 2b/3 Study ANAVEX2-73-AD-004

This is a Phase 2b/3 open-label extension study to evaluate the effects of ANAVEX2-73 on safety and effficacy of daily treatment.

Kawartha Centre
 (0.2 away) Contact site
  • 42 views
  • 13 Apr, 2021
  • +49 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

infarct
stemi
acute coronary syndrome
diabetes
myocardial infarction
1240078 - Kawartha Cardiology Clinical Trials
 (0.6 away) Contact site
  • 1131 views
  • 22 Sep, 2021
  • +3432 other locations
Long-Term PF-06651600 for the Treatment of Alopecia Areata

This is a global Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called PF-06651600) in adults and adolescents (12 years and older) who have alopecia areata. Eligible patients from the prior studies B7931005 (NCT02974868) and B7981015 (NCT03732807) will have an opportunity to enroll as …

androgenic alopecia
alopecia totalis
alopecia universalis
alopecia
areata alopecia
SKiN Centre for Dermatology
 (1.9 away) Contact site
  • 1581 views
  • 22 Sep, 2021
  • +177 other locations
ANAVEX2-73 for Treatment of Early Alzheimer's Disease

Phase 2b/3 48-week study to evaluate the effects of ANAVEX2-73 on cognition and function after 48 weeks of daily treatment. Additional outcome measures include refined measures of sleep, behavioral and psychological symptoms typically observed in AD, changes in daily functioning of participants and changes in caregiver burden, as well as …

cognitive assessment
amyloidosis
psychological symptoms
mini-mental state examination
cognitive impairment
Kawartha Centre
 (0.0 away) Contact site
  • 250 views
  • 09 May, 2021
  • +53 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

cardiovascular disease
overweight or obesity
body mass index
Novo Nordisk Investigational Site
 (0.6 away) Contact site
  • 7778 views
  • 22 Sep, 2021
  • +1166 other locations
A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation

This is a randomized, double-blind, placebo-controlled study in patients with dilated cardiomyopathy (DCM) due to a mutation of the gene encoding the lamin A/C protein (LMNA). The study will further evaluate a dose level of study drug (ARRY-371797) that has shown preliminary efficacy and safety in this patient population. After …

c protein
arry-371797
implantable cardioverter defibrillator
cardiac resynchronization therapy
dilated cardiomyopathy
Array Investigative Site
 (0.0 away) Contact site
  • 421 views
  • 05 Sep, 2021
  • +261 other locations
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

plaque psoriasis
mirikizumab
SKiN Centre for Dermatology
 (1.9 away) Contact site
  • 717 views
  • 22 Sep, 2021
  • +361 other locations