Ottowa, Canada Clinical Trials

A listing of Ottowa, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 118 clinical trials
Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients

The purpose of this study is to determine whether PXT3003 is effective and safe in the treatment of Charcot-Marie-Tooth disease - Type 1A. This double-blind study will assess in parallel groups 1 dose of PXT3003 compared to Placebo in CMT1A patients treated for 15 months.

Ottawa Hospital Research Institute Civic Campus
 (2.3 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +62 other locations
Long-term Safety and Efficacy of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema Attacks

This phase 3b study will evaluate long-term safety and efficacy of CSL312 (also known as garadacimab) when administered subcutaneously (SC)

angioedema
Ottawa Allergy Research Corp
 (5.4 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +15 other locations
A Study of Benralizumab in Patients With Eosinophilic Esophagitis

The aim of this Phase 3 study is to investigate the use of benralizumab as a treatment for patients with EoE. The effect of doses of benralizumab on EoE histologic signs and symptoms will be assessed over a 52-week treatment period (including a 24-week double-blind placebo-controlled treatment period and a …

Research Site
 (5.4 away) Contact site
  • 3 views
  • 27 Sep, 2021
  • +86 other locations
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG).

weakness
generalized myasthenia gravis
The Ottawa Hospital Research Institute
 (2.7 away) Contact site
  • 4 views
  • 27 Sep, 2021
  • +145 other locations
OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)

A 2-year phase 3, multicentre, randomised, parallel-group, sham-controlled, double-masked study. Primary efficacy will be determined at Week 52.

COAST Investigational Site
 (5.1 away) Contact site
  • 3 views
  • 24 Sep, 2021
  • +61 other locations
A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

Study CC-93538-EE-001 is a Phase 3, multicenter, multinational, randomized, double-blind, placebo-controlled induction and maintenance study to evaluate the efficacy and safety of CC- 93538 in adult and adolescent participants with eosinophilic esophagitis (EoE). The study will incorporate a 24-week Induction Phase followed by a 24-week Maintenance Phase. Participants will be …

Ottawa Allergy Research Corporation
 (5.4 away) Contact site
  • 42 views
  • 26 Sep, 2021
  • +228 other locations
Comparing Hypothermic Temperatures During Hemiarch Surgery

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend …

University of Ottawa Heart Institute
 (2.2 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +4 other locations
A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

This is a Phase 1/2, open-label, multiple-dose, dose-escalating study to evaluate the safety, tolerability, and plasma and cerebrospinal fluid (CSF) concentrations of GTX-102 in pediatric patients with Angelman syndrome. Up to 20 patients (male and female) 4 and 17 years of age with a genetically confirmed diagnosis of full maternal …

Children's Hospital of Eastern Ontario
 (2.5 away) Contact site
  • 0 views
  • 24 Sep, 2021
  • +5 other locations
Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects 1 Month to <17 Years Undergoing MRI Scans

This is a randomized, double-blind, dose-ranging study of the efficacy and safety of dexmedetomidine (DEX) when used with propofol as needed, for procedural sedation of pediatric subjects 1 month to <17 years of age undergoing MRI scans in the US and Japan.

Children's Hospital of Eastern Ontario
 (2.5 away) Contact site
  • 5 views
  • 26 Sep, 2021
  • +37 other locations
An Attachment Based Approach for Anxiety and Depression

The purpose of the current study is to examine the efficacy of Emotionally Focused Therapy for Individuals (EFIT) as a treatment for depression and anxiety. It is formulated as a trans-diagnostic treatment in line with the call for more transdiagnostic approaches to treat depression and anxiety given the many similarities …

Saint Paul University
 (1.3 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +2 other locations