Ottowa, Canada Clinical Trials

A listing of Ottowa, Canada clinical trials actively recruiting patients volunteers.

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Found 47 clinical trials
Featured trial
Sickle Cell Disease Study: Own Your Health, Share Your Story with PicnicHealth

Get all of your medical records in one secure account and contribute to important real-world Sickle Cell research with PicnicHealth. If you have Sickle Cell, you get $50 for signing up and a free lifetime access to your medical records.   Visit this link to learn more and sign up. …

Online studies
PicnicHealth
(online study) Contact site
  • 11 views
  • 04 Aug, 2022
  • 1 location
  • Online study
Featured trial
Caregiver-Provided Life Review for Persons with Dementia

This study, Caregiver-Provided Life Review (C-PLR) is created based on Life Review therapy. It is for persons living with early-stage dementia along with mild depressive symptoms who are 65 years or older, community-dwellers or the residents of senior housing, independent or assisted living facilities conducted by their family members (18 …

Accepts healthy volunteers
depression
Online studies
dementia
Online Study Center
(online study) Contact site
  • 547 views
  • 09 Aug, 2022
  • 1 location
  • Online study
Featured trial
Family and Caregiver Perspective on Gene Therapy for Rett Syndrome

If you or someone you know would be interested in participating in an online survey, please visit https://bit.ly/3viVFxBThe purpose of this study is to assess the attitudes and opinions of parents, siblings, caregivers, and legal guardians of individuals with Rett syndrome about gene therapy. The study is available for individuals living …

Online studies
University of Arizona
(online study) Contact site
  • 0 views
  • 02 Aug, 2022
  • 1 location
  • Online study
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) (VISTAS)

The purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Sclerosing Cholangitis (PSC), and to assess the possible impact on the disease progression of PSC.

The Ottawa Hospital - General Campus
 (2.7 away) Contact site
  • 0 views
  • 11 Aug, 2022
  • +36 other locations
RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)

To evaluate the treatment effect of seladelpar on composite biochemical improvement in cholestasis markers based on ALP and total bilirubin and to evaluate the safety of seladelpar over 12 months of treatment compared to placebo

The Ottawa Hospital
 (2.3 away) Contact site
  • 5 views
  • 08 Aug, 2022
  • +157 other locations
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study (study number PD0053) is a clinical research study for people with early-stage Parkinson’s disease (<2 years). The aim of the study is to find out whether an investigational medication known as UCB0599 can slow the progression of Parkinson’s disease and whether it is efficacious and well tolerated (which means …

dopamine transporter
bradykinesia
motor symptoms
resting tremor
tremor
Ottawa Hospital - Civic Campus
 (2.3 away) Contact site
  • 326 views
  • 09 Aug, 2022
  • +64 other locations
Safety and Efficacy Study Of CFI-402411 in Subjects With Advanced Solid Malignancies

The purpose of this study is to test the safety of an investigational drug called CFI-402411 alone and in combination with pembrolizumab and to study its effects in patients with advanced solid tumors who have progressed following previous therapies.

The Ottawa Hospital
 (2.3 away) Contact site
  • 102 views
  • 08 Aug, 2022
  • +11 other locations
A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome (KIK-AS)

The primary objective of the study is to evaluate the safety and tolerability of multiple-ascending doses of GTX-102 administered by IT injection to patients with AS.

Children's Hospital of Eastern Ontario
 (2.5 away) Contact site
  • 198 views
  • 09 Aug, 2022
  • +6 other locations
TRILUMINATE Pivotal Trial

The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or greater estimated risk for mortality or morbidity with tricuspid valve surgery. This randomized controlled trial will …

tricuspid valve repair
medical therapy
repair of tricuspid valve
diuretics
regurgitation
Ottawa Heart Institute
 (2.2 away) Contact site
  • 156 views
  • 10 Aug, 2022
  • +79 other locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating …

cyclophosphamide
MRI
vincristine
glomerular filtration rate
seizure
Children's Hospital of Eastern Ontario
 (2.5 away) Contact site
  • 217 views
  • 11 Aug, 2022
  • +126 other locations