North York, Canada Clinical Trials

A listing of North York, Canada clinical trials actively recruiting patients volunteers.

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Found 1263 clinical trials
Cognitive Impairment Registry

The purpose of this study is to develop a recruitment registry of potential drug study participants who may have amyloid, a specific biomarker for Alzheimer's disease, using a phone assessment of cognitive and behavioral functions. The investigator uses the responses to the phone questions to predict which participants most likely …

amyloid
Accepts healthy volunteers
Online studies
Online Study Center
(online study) Contact site
  • 992 views
  • 23 Sep, 2022
  • 1 location
  • Online study
Objective, Passive Assessment of LRRK2 Carriers (OPAL)

This study is currently only open to active participants in the University of Rochester’s VALOR-PD study. The goal of this project is to identify objective, sensitive, and convenient measures for assessing early signs of Parkinson's disease in an at-risk population at home. We will do so by using a wireless …

movement disorder
Online studies
University of Rochester
(online study) Contact site
  • 64 views
  • 12 May, 2022
  • 1 location
  • Online study
Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)

Double-blind, randomized, placebo-controlled, Phase 3 study to investigate the efficacy and safety of odevixibat compared to placebo in children with biliary atresia who have undergone a Kasai hepatoportoenterostomy.

The Hospital for Sick Children
 (7.3 away) Contact site
  • 0 views
  • 30 May, 2022
  • +70 other locations
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab (ARTIOS)

Open-label study to evaluate the effectiveness of treatment with ofatumumab in subjects transitioning from any fumarate-based RMS approved therapy or fingolimod due to breakthrough disease.

dimethyl fumarate
ofatumumab
fingolimod
Novartis Investigative Site
 (3.2 away) Contact site
  • 183 views
  • 12 Jul, 2022
  • +136 other locations
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus (TN-22)

The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.

The Hospital For Sick Kids
 (7.3 away) Contact site
  • 694 views
  • 13 Feb, 2022
  • +50 other locations
PSMA-PET Registry for Recurrent Prostate Cancer (PREP)

This study aims to institute a province-wide registry leveraging the availability of a new Positron Emission Tomography tracer, [18F]-DCFPyL and PET expertise across Ontario centers to improve our ability to characterize patterns of recurrence and personalize therapies in men with recurrent prostate cancer after primary treatment.

bone scan
prostatectomy
positron emission tomography
karnofsky performance status
ct scan
Toronto Sunnybrook Cancer Centre
 (3.2 away) Contact site
  • 108 views
  • 15 Feb, 2022
  • +5 other locations
Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) (PITSTOP)

Sepsis occurs when a serious infection - most commonly infection of the lungs, urinary system, or blood - leads to acute organ failure. It is a common, expensive, and frequently lethal condition. A growing body of evidence suggests that early recognition and treatment of sepsis can improve survival. Unfortunately, many …

Halton Region Paramedic Services
 (7.6 away) Contact site
  • 9 views
  • 05 Mar, 2022
  • 1 location
SAHaRA: A Randomized Controlled Trial

The SAHaRA trial will clarify the role of treating anemia with Red Blood Cell (RBC) transfusion in a unique and vulnerable patient population, and determine whether that impacts on functional outcomes and mortality. It will guide best practice standards and clarify the optimal RBC transfusion strategy in patients with aSAH.

Sunnybrook Research Institute
 (3.2 away) Contact site
  • 364 views
  • 02 Mar, 2022
  • +16 other locations
RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy (BREVITY)

The current study aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsies taken starting from 35 +/- 4 days after the initiation of neoadjuvant chemotherapy.

invasive breast cancer
breast cancer
cancer
adjuvant therapy
Sunnybrook Health Sciences Center
 (3.2 away) Contact site
  • 33 views
  • 09 Jul, 2022
  • +5 other locations
ADCC Mediated B-Cell dEpletion and BAFF-R Blockade (AMBER)

VAY736 dose testing; VAY736 efficacy and safety testing.

adcc
Novartis Investigative Site
 (7.2 away) Contact site
  • 135 views
  • 13 Jul, 2022
  • +42 other locations