North Vancouver, Canada Clinical Trials

A listing of North Vancouver, Canada clinical trials actively recruiting patients volunteers.

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Found 45 clinical trials
Featured trial
Caregiver-Provided Life Review for Persons with Dementia

This study, Caregiver-Provided Life Review (C-PLR) is created based on Life Review therapy. It is for persons living with early-stage dementia along with mild depressive symptoms who are 65 years or older, community-dwellers or the residents of senior housing, independent or assisted living facilities conducted by their family members (18 …

Online studies
dementia
depression
Accepts healthy volunteers
Online Study Center
(online study) Contact site
  • 566 views
  • 09 Aug, 2022
  • 1 location
  • Online study
Featured trial
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
British Columbia Cancer Agency
 (4.5 away) Contact site
  • 36 views
  • 10 Aug, 2022
  • +82 other locations
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer (EV-302)

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients in this study will have …

carcinoma
measurable disease
carboplatin
metastatic urothelial carcinoma
gemcitabine
Site CA11006
 (4.5 away) Contact site
  • 121 views
  • 11 Aug, 2022
  • +190 other locations
A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer (CREST)

The purpose of this study is to learn about the safety and effects of the study medicine (sasanlimab) in people with non-muscle invasive bladder cancer. This study is seeking participants whose bladder cancer is still in early stages, has not spread outside of the bladder, has been removed with surgery, …

Vancouver Prostate Centre at the Vancouver General Hospital
 (4.6 away) Contact site
  • 93 views
  • 08 Aug, 2022
  • +172 other locations
A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2)

The purpose of this study is to assess the efficacy of lazertinib, amivantamab, carboplatin, and pemetrexed (LACP) and amivantamab, carboplatin and pemetrexed (ACP) compared with carboplatin and pemetrexed (CP), respectively, in participants with locally advanced or metastatic epidermal growth factor receptor (EGFR) Exon 19del or Exon 21 L858R substitution non-small …

epidermal growth factor
measurable disease
growth factor
kinase inhibitor
carboplatin
British Columbia Cancer Agency
 (4.5 away) Contact site
  • 11 views
  • 10 Aug, 2022
  • +207 other locations
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.

Arc Biosystems
 (3.8 away) Contact site
  • 6 views
  • 10 Aug, 2022
  • +40 other locations
HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants (ESTHI)

Hydrocephalus is a potentially debilitating neurological condition that primarily affects babies under a year of age and has traditionally been treated by inserting a shunt between the brain and the abdomen. A newer endoscopic procedure offers hope of shunt- free treatment that may reduce complications over a child's life, but …

ventriculoperitoneal shunt
endoscopic third ventriculostomy
endoscopic procedure
hcrn
hydrocephalus in infants
British Columbia Children's Hospital
 (5.7 away) Contact site
  • 0 views
  • 11 Aug, 2022
  • +15 other locations
A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence

The purpose of the study is to evaluate the safety and effects of onabotulinumtoxinA (BOTOX) for the temporary improvement in the appearance of platysma prominence. Study doctors will randomize participants into 1 of the 2 groups, called treatment arms. There is a 1 in 2 chance that a participant will …

Humphrey Cosmetic Dermatology /ID# 229522
 (4.5 away) Contact site
  • 179 views
  • 10 Aug, 2022
  • +28 other locations
A Study to Assess Adverse Events and Change in Disease Activity of Intramuscular AGN-151586 Injection in Toxin-Naïve Adult Participants With Glabellar Lines

Facial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. AGN-151586 is an investigational product being developed for the treatment of GL. The purpose of this study is to evaluate the safety and …

Pacific Derm /ID# 239654
 (4.8 away) Contact site
  • 3 views
  • 09 Aug, 2022
  • +12 other locations
TRILUMINATE Pivotal Trial

The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or greater estimated risk for mortality or morbidity with tricuspid valve surgery. This randomized controlled trial will …

heart failure
tricuspid valve repair
diuretics
mitral regurgitation
regurgitation
St. Paul's Hospital
 (3.8 away) Contact site
  • 156 views
  • 10 Aug, 2022
  • +79 other locations