Newmarket, Canada Clinical Trials

A listing of Newmarket, Canada clinical trials actively recruiting patients volunteers.

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Found 21 clinical trials
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Novartis Investigative Site
 (23.6 away) Contact site
  • 211 views
  • 17 Jul, 2021
  • +362 other locations
Study of Verinurad in Heart Failure With Preserved Ejection Fraction

International, Multicenter, Double-Blind, Placebo and Active Control Efficacy and Safety Study to Evaluate Verinurad combined with Allopurinol in Heart Failure with Preserved Ejection Fraction

Research Site
 (0.5 away) Contact site
  • 0 views
  • 16 Jul, 2021
  • +89 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

plaque psoriasis
apremilast
risankizumab
arthritis
systemic therapy
Dr. S.K. Siddha Medicine Professional Corporation /ID# 230416
 (0.6 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +61 other locations
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for …

x-rays
cancer treatment
exercise intervention
cancer
colon cancer
Stronach Regional Health Centre at Southlake
 (0.5 away) Contact site
  • 397 views
  • 23 Jul, 2021
  • +50 other locations
Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients

This is a global, Phase 3b, multicenter, open-label, single-arm study to evaluate the safety and efficacy of acalabrutinib 100 mg bid in approximately 600 participants with chronic lymphocytic leukemia (CLL). Participants will be enrolled into 3 cohorts: treatment-naive (TN), relapsed/refractory (R/R), and prior Bruton tyrosine kinase inhibitor (BTKi) therapy. Participants …

night sweats
recurrent chronic lymphocytic leukemia
tyrosine
fever
lymphocytosis
Research Site
 (0.5 away) Contact site
  • 275 views
  • 25 Jul, 2021
  • +159 other locations
Durvalumab Long-Term Safety and Efficacy Study

The aims of the study are to monitor the long-term safety of durvalumab, to provide continued treatment or retreatment with durvalumab to eligible patients, and to collect overall survival (OS) information.

antineoplastic
cancer treatment
Research Site
 (0.5 away) Contact site
  • 23 views
  • 20 Jul, 2021
  • +176 other locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

muscarinic antagonists
copd exacerbation
albuterol
corticosteroids
cigarette smoke
GSK Investigational Site
 (0.6 away) Contact site
  • 379 views
  • 24 Jul, 2021
  • +232 other locations
Linaclotide Safety and Efficacy in Pediatric Participants 6 to 17 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)

The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 g daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria for Child/Adolescent Functional Constipation (FC). The objective of LIN-MD-64 is to …

laxative
posturing
incontinence
SKDS Research Inc
 (0.6 away) Contact site
  • 136 views
  • 17 Jul, 2021
  • +284 other locations
Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

The study is a prospective, multi-center, non-randomized, unblinded worldwide pre-market clinical study. The purpose of the study is to provide data demonstrating the safety and effectiveness of the PulseSelect PFA System for the treatment of atrial fibrillation (AF). The study will also provide first in human insights into clinical safety …

pulmonary vein isolation
fibrillation
antiarrhythmic drug
Cleveland Clinic
 (197.8 away) Contact site
  • 16 views
  • 25 Jul, 2021
  • +28 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
florbetapir
positron emission tomography
mini-mental state examination
alzheimer's disease
SKDS Research Inc.
 (0.6 away) Contact site
  • 79 views
  • 24 Jul, 2021
  • +389 other locations