Newmarket, Canada Clinical Trials

A listing of Newmarket, Canada clinical trials actively recruiting patients volunteers.

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Found 43 clinical trials
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Novartis Investigative Site
 (23.6 away) Contact site
  • 211 views
  • 17 Jul, 2021
  • +362 other locations
Study of Verinurad in Heart Failure With Preserved Ejection Fraction

International, Multicenter, Double-Blind, Placebo and Active Control Efficacy and Safety Study to Evaluate Verinurad combined with Allopurinol in Heart Failure with Preserved Ejection Fraction

Research Site
 (0.5 away) Contact site
  • 0 views
  • 16 Jul, 2021
  • +89 other locations
Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack

The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of a dual antiplatelet therapy (acetylsalicylic acid +/- clopidogrel) in patients following a recent heart attack …

clopidogrel
ck-mb
antiplatelet therapy
aspirin
troponin
York PCI Group Inc.
 (0.4 away) Contact site
  • 57 views
  • 08 Jul, 2021
  • +192 other locations
Efficacy and Safety of Etripamil for the Termination of Spontaneous PSVT. NODE 301 [Part 1 and Part 2 (The RAPID Study)]

This is a two-part, multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of etripamil NS self-administered by patients who experience an episode of paroxysmal ventricular tachycardia (PSVT) in an at-home setting. Part 1 comprised the conduct of the NODE-301 study up to the date of the adjudication …

St. Michael's Hospital
 (28.2 away) Contact site
  • 281 views
  • 05 May, 2021
  • +127 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

risankizumab
apremilast
systemic therapy
arthritis
plaque psoriasis
Dr. S.K. Siddha Medicine Professional Corporation /ID# 230416
 (0.6 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +61 other locations
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

This study aims to determine if treatment with apixaban, compared with aspirin, will reduce the risk of ischemic stroke and systemic embolism in patients with device-detected sub-clinical atrial fibrillation and additional risk factors for stroke.

cardiac monitoring
aspirin
apixaban
vascular disease
embolism
St. Michael's Hospital
 (28.2 away) Contact site
  • 337 views
  • 26 Jan, 2021
  • +131 other locations
Optimal Anticoagulation for Higher Risk Patients Post-Catheter Ablation for Atrial Fibrillation Trial

This trial is comparing medical approaches for stroke prevention in people who have atrial fibrillation (AF) and have undergone a successful procedure called ablation to eliminate or substantially reduce the arrhythmia. AF is normally associated with an increased risk of stroke which in many patients can be prevented with appropriate …

anticoagulants
anticoagulation therapy
anticoagulant therapy
aspirin
vascular disease
St. Michael's Hospital
 (28.2 away) Contact site
  • 200 views
  • 21 Mar, 2021
  • +58 other locations
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for …

fatigue
cancer treatment
colon cancer
fatigue assessment and management
cancer
Stronach Regional Health Centre at Southlake
 (0.5 away) Contact site
  • 397 views
  • 23 Jul, 2021
  • +50 other locations
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack in the prior 5 years, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.

stemi
coronary angioplasty
ace inhibitor
revascularisation
coronary artery bypass graft
Southlake
 (0.5 away) Contact site
  • 258 views
  • 21 Jan, 2021
  • +82 other locations
Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients

This is a global, Phase 3b, multicenter, open-label, single-arm study to evaluate the safety and efficacy of acalabrutinib 100 mg bid in approximately 600 participants with chronic lymphocytic leukemia (CLL). Participants will be enrolled into 3 cohorts: treatment-naive (TN), relapsed/refractory (R/R), and prior Bruton tyrosine kinase inhibitor (BTKi) therapy. Participants …

night sweats
lymphadenopathy
lymphoid leukemia
fatigue
recurrent chronic lymphocytic leukemia
Research Site
 (0.5 away) Contact site
  • 275 views
  • 25 Jul, 2021
  • +159 other locations