New Westminster, Canada Clinical Trials

A listing of New Westminster, Canada clinical trials actively recruiting patients volunteers.

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Found 112 clinical trials
PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2 (PERK2)

PrEvention of posttraumatic contractuRes with Ketotifen 2 (PERK 2) is a Phase III randomized, controlled, double blinded multicenter trial with 3 parallel groups (Ketotifen 2 mg or 5 mg or lactose placebo twice daily orally for 6 weeks) and a primary endpoint of elbow extension-flexion range of motion (ROM) arc …

Royal Columbia Hospital
 (1.7 away) Contact site
  • 60 views
  • 16 Oct, 2022
  • +14 other locations
A Phase 1/2, Open-Label, Multi-Center, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of TPX-0005 in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1) (TRIDENT-1)

Phase 1 dose escalation will determine the first cycle dose-limiting toxicities (DLTs), the maximum tolerated dose (MTD), the biologically effective dose and recommended Phase 2 dose (RP2D) of repotrectinib given to adult subjects with advanced solid malignancies harboring an ALK, ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. Midazolam DDI substudy …

solid tumor
cancer
ROS1
BC Cancer PHASE 2
 (9.9 away) Contact site
  • 369 views
  • 18 Oct, 2022
  • +145 other locations
Induction Study #2 - A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

endoscopy
immunomodulators
abdominal pain
ileal disease
crohn's disease
Fraser Clinical Trials Inc.
 (1.6 away) Contact site
  • 550 views
  • 22 Oct, 2022
  • +356 other locations
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a study to demonstrate the effect of oral ozanimod as maintenance therapy in participants with moderately to severely active Crohn's Disease.

abdominal pain
crohn's disease
remission
Fraser Clinical Trials Inc.
 (1.6 away) Contact site
  • 1028 views
  • 22 Oct, 2022
  • +489 other locations
ACURATE IDE: Transcatheter Replacement of Stenotic Aortic Valve Through Implantation of ACURATE in Subjects InDicatEd for TAVR

To evaluate safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for transcatheter aortic valve replacement (TAVR) in subjects with severe native aortic stenosis who are indicated for TAVR.

left ventricular dysfunction
aortic valve stenosis
dobutamine
cancer
aortic valve replacement
Royal Columbian Hospital
 (1.7 away) Contact site
  • 85 views
  • 24 Oct, 2022
  • +84 other locations
EMPACT-MI: A Streamlined, Multicentre, Randomised, Parallel Group, Double-blind Placebo-controlled Superiority Trial to Evaluate the Effect of EMPAgliflozin on Hospitalisation for Heart Failure and Mortality in Patients With aCuTe Myocardial Infarction

This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying …

revascularisation
heart failure
stemi
acute myocardial infarction
myocardial infarction
Surrey Memorial Hospital
 (3.7 away) Contact site
  • 204 views
  • 24 Oct, 2022
  • +436 other locations
A Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Finerenone on Morbidity and Mortality in Participants With Heart Failure (NYHA II-IV) and Left Ventricular Ejection Fraction ≥ 40% (LVEF ≥ 40%) (FINEARTS-HF)

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

heart failure
nt-probnp
stroke
natriuretic peptide
heart disease
Fraser Clinical Trials, Inc.
 (1.6 away) Contact site
  • 97 views
  • 24 Oct, 2022
  • +587 other locations
Anterior Cruciate Ligament Reconstruction Using Bone Patellar Bone or Quad Tendon Autograft With or Without Lateral Extra-Articular Tenodesis in Individuals Who Are at High Risk of Graft Failure (STABILITY 2) (STABILITY 2)

Anterior cruciate ligament (ACL) rupture is one of the most common musculoskeletal injuries in young individuals, particularly those that are active in sports. Up to 30% of individuals under the age of 20 years suffer a re-injury to the reconstructed ACL. Revision ACLR has been associated with degeneration of the …

joint laxity
ligament reconstruction
injuries
autograft
meniscal tear
Fraser Health Authority
 (1.0 away) Contact site
  • 55 views
  • 14 Oct, 2022
  • +16 other locations
A Phase 2, Multicenter, Double-Blind, Placebo-Controlled, Multiple-Cohort Study Investigating the Effect of EDP1815 in Participants for the Treatment of Mild, Moderate and Severe Atopic Dermatitis

The purpose of this research study is to determine whether the study drug, EDP1815, is safe and effective in the treatment of atopic dermatitis compared with placebo. The study will look at different doses of the study drug, and whether there are differences when the drug is given once daily …

CAN-103
 (3.0 away) Contact site
  • 0 views
  • 14 Oct, 2022
  • +53 other locations
A Phase 3, Multicenter, Open-Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is an extension study to evaluate safety and efficacy of ozanimod in participants with moderately to severely active Crohn's Disease.

crohn's disease
remission
Fraser Clinical Trials Inc.
 (1.6 away) Contact site
  • 1144 views
  • 18 Oct, 2022
  • +501 other locations