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Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

RESULTS

Found (429) clinical trials

Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi

This is a multicentre, open-label, randomized controlled trial in 160 patients with recently-diagnosed T2DM. Participants will be randomized to 2 treatment groups: (a) a 12-week course of treatment with iGlarLixi, metformin and lifestyle therapy, and (b) standard diabetes therapy, and followed for a total of 64 weeks (1 year and ...

Phase

4.01 miles

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Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback

The investigators aim to assess the impact of benchmarked and ranked feedback on anesthesiologists' perioperative temperature management and subsequent patient outcomes.

Phase N/A

4.01 miles

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Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial

Background:Probiotics are live microorganisms thought to have health benefits when ingested. Randomized controlled trials (RCTs) have documented favourable impact on a range of clinical problems, including prevention of upper respiratory tract infections, antibiotic-associated diarrhea, Clostridium difficile-associated diarrhea, and irritable bowel syndrome. Our recent meta-analysis of probiotic RCTs in the intensive ...

Phase

4.01 miles

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Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's

This is a prospective, multi-centre, pragmatic randomized controlled trial to compare both the clinical effectiveness and cost-effectiveness of collagenase injections (CI) versus limited palmar fasciectomy (LPF) to determine if collagenase is a superior treatment in terms of improved quality of life and reducing recurrence of the disease without serious complications. ...

Phase

4.01 miles

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Evaluating the Efficacy of E-Cigarette Use for Smoking Cessation (E3) Trial

I. OVERALL STUDY OBJECTIVE The Evaluating the Efficacy of E-Cigarette use for Smoking Cessation (E3) Trial is a 5-year, multi-centre, randomized controlled trial (RCT) that seeks to assess the efficacy, safety, and tolerability of nicotine and non-nicotine electronic cigarettes (e-cigarettes) for smoking cessation in the general population. II. SPECIFIC OBJECTIVES ...

Phase

4.01 miles

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Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia

Male and female subjects aged 18 years or older will be randomized to receive either open surgical treatment or endovascular treatment. They will be followed for at least 2 years and up to 4 years and 2 months after treatment to primarily assess survival and major adverse limb events in ...

Phase N/A

4.01 miles

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Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease

To assses if Glycopyrrolate has a long lasting effect on sialorrhea for patients with Parkinsons.

Phase

4.01 miles

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Examining Effects of Spinal Fusion on Outcomes Following Total Hip Replacement

The purpose of the study is to explore the long term functional status of people who have had both a spinal fusion procedure and a total hip replacement. Studies have found that those who have received spinal fusion may have worse outcomes following a total hip replacement than those who ...

Phase N/A

4.01 miles

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SAHaRA: A Randomized Controlled Trial

We hypothesize that in adult patients suffering from aSAH and anemia, a liberal RBC transfusion strategy as compared to a restrictive RBC transfusion strategy decreases the combined rate of death and severe disability at 12 months (using the modified Rankin Scale)

Phase

4.01 miles

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Personalized Dosing of Nicotine Replacement (NRT to Effect)

A total of 500 smokers will be enrolled from two smoking cessation clinics to participate in this study. After 2 weeks of usual treatment with 21mg patch, participants who fail to quit smoking will be randomized to receive either escalating doses of active nicotine patches, or placebo patches, for 10 ...

Phase

4.01 miles

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