Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

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Found 484 clinical trials
Prednisone in Cystic Fibrosis Pulmonary Exacerbations

This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a pulmonary exacerbation at the Hospital for Sick Children and other study sub-sites across Canada. The intervention will be oral prednisone …

The Ottawa Hospital
 (4.0 away) Contact site
  • 32 views
  • 19 Jun, 2021
  • +11 other locations
Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation

Continuous-flow left ventricular assist devices (LVAD) move blood from the left ventricle (the largest chamber of the heart) to the aorta (the body's main artery) to help the heart better meet the needs of the body and to improve survival for patients with advanced heart failure (HF). The ability of …

University of Ottawa Heart Institute
 (4.1 away) Contact site
  • 26 views
  • 08 May, 2021
  • +3 other locations
CT-Perfusion for Neurological Diagnostic Evaluation

For the purpose of organ donation after neurological determination of death (NDD), death must be declared using a set of standardized clinical criteria. When a full clinical evaluation cannot be completed, additional neuroimaging ancillary testing is required. The ideal ancillary test for NDD would demonstrate no cerebral blood flow, be …

The Ottawa Hospital
 (6.1 away) Contact site
  • 727 views
  • 01 Aug, 2021
  • +18 other locations
Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging

Bladder cancer is the fifth most common cancer in Canada and there has been relatively little progress in altering its clinical course over the last three decades. One of the major problems identified in the management of this disease, is under staging of muscle invasive disease which can lead to …

Ottawa Hospital Regional Cancer Centre
 (5.8 away) Contact site
  • 14 views
  • 26 Jan, 2021
  • +5 other locations
Parent Therapist Partnership to Provide Early Intensive Exercise in Perinatal Stroke

A prospective, single blind, parallel group, randomized control trial to determine if early, intensive leg exercise delivered by a physical therapist and a parent in combination improves gross motor function more than standard of care.

Children's Hospital of Eastern Ontario
 (6.1 away) Contact site
  • 19 views
  • 25 Jan, 2021
  • +2 other locations
Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery

Post-operative urinary retention (POUR) is a frequent complication reported as ranging from 10 to 55% in the literature. In a recent retrospective study from Laliberte et al in Quebec City, we observed that 19% of the patients operated using transanal endoscopic microsurgery (TEM) had a post-operative urinary retention (POUR). Factors …

Ottawa Hospital Research Institute
 (4.0 away) Contact site
  • 284 views
  • 28 May, 2021
  • +2 other locations
Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors Including Central Nervous System Tumors

Phase 1 of this study, utilizing a rolling 6 design, will be conducted to determine a maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), and to describe the toxicities of lenvatinib administered in combination with everolimus once daily to pediatric participants with recurrent/refractory solid tumors. Phase 2, utilizing …

Children's Hospital of Eastern Ontario
 (5.8 away) Contact site
  • 0 views
  • 09 Aug, 2021
  • +56 other locations
Stem Cell Mobilization by G-CSF Post Myocardial Infarction to Promote Myocyte Repair

Eighty-six patients with heart attacks will be identified at our hospital. Post heart attack we will assess heart function, blood flow to the heart, and heart cell function. We will assess these parameters using nuclear cardiology scans that are used in everyday cardiology practice. The patients will then be divided …

angiography
heart disease
cancer
University of Ottawa Heart Institute
 (4.1 away) Contact site
  • 54 views
  • 07 Nov, 2020
  • 1 location
A Phase I/II Study of Concurrent Pemetrexed/Cisplatin/Radiation in Stage IIIA/B Non-Small Cell Lung Cancer

The purpose of this study is to determine the safety and efficacy of the combination of pemetrexed and cisplatin given concurrently with high dose radiation treatment in patients with unresectable but potentially curable stage IIIA/B non-small cell lung cancer.

pemetrexed
Ottawa Regional Cancer Centre
 (6.1 away) Contact site
  • 32 views
  • 07 Nov, 2020
  • 1 location
Cortisol Response to Adrenocorticotrophin (ACTH) in Acute Stress

Cortisol deficiency is diagnosed by the adrenocorticotrophin (ACTH) stimulation test. This test measures cortisol levels in the blood before and after giving an injection of ACTH. Currently, the results of this test can only be reliably interpreted when it is carried out on people in non-stressful situations. Frequently the test …

open repair
aortic aneurysm
The Ottawa Hospital, Riverside campus
 (5.1 away) Contact site
  • 58 views
  • 07 Nov, 2020
  • 1 location