Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

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Found 482 clinical trials
Long-term Safety Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have participated in a Novartis ofatumumab clinical MS study. Vaccination sub-study The purpose of this research sub-study is to find out the effects of ofatumumab on the development of antibody …

tetanus
pneumococcal conjugate vaccine
ofatumumab
Novartis Investigative Site
 (5.8 away) Contact site
  • 247 views
  • 11 Sep, 2021
  • +261 other locations
Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion

Coronary angiography is performed to evaluate for obstructive coronary artery disease. This is commonly performed via the transfemoral or transradial approach with the latter increasing in frequency. One of the most common complications of transradial access is radial artery occlusion occurring in ~5% of patients which prohibits the use of …

University of Ottawa Heart Institute
 (4.1 away) Contact site
  • 11 views
  • 26 Jan, 2021
  • 1 location
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus

The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.

Children's Hospital of Eastern Ontario
 (5.8 away) Contact site
  • 221 views
  • 06 Aug, 2021
  • +48 other locations
Efficacy Safety and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.

This clinical study will test the effects of a drug called apremilast in oligoarticular psoriatic arthritis with less than 5 years of disease duration. In previous studies, apremilast has been shown to be safe and efficacious in reducing signs and symptoms of psoriatic arthritis, as well as improving physical function. …

apremilast
Ottawa Hospital
 (4.0 away) Contact site
  • 279 views
  • 08 Aug, 2021
  • +268 other locations
Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

This is a randomized, double-blind, study that compares pembrolizumab (MK-3475) with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in …

pembrolizumab
mk-3475
cancer
adjuvant therapy
The Ottawa Hospital Cancer Centre ( Site 0154)
 (5.8 away) Contact site
  • 79 views
  • 19 Sep, 2021
  • +146 other locations
A Study of Biomarker-Directed Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)

This study will investigate the utility of biomarker-based triage for study participants with advanced non-small cell lung cancer (NSCLC) without prior systemic therapy. Study participants within groups defined by a biomarker-based classifier (gene expression profile [GEP] and tumor mutational burden [TMB]) will be randomized to receive pembrolizumab in combination with …

The Ottawa Hospital - Cancer Care ( Site 0306)
 (5.8 away) Contact site
  • 360 views
  • 04 Sep, 2021
  • +93 other locations
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determining the superiority of lecanemab compared with placebo on the change from baseline in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) at 18 months of treatment in the Core Study. This …

Recherches Neuro-Hippocampe, Inc., d/b/a Ottawa Memory Clinic
 (3.3 away) Contact site
  • 245 views
  • 05 Jul, 2021
  • +275 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (2.3 away) Contact site
  • 37 views
  • 08 Sep, 2021
  • +477 other locations
TSA vs RSA in Osteoarthritis

This study will compare total shoulder arthroplasty (TSA) reverse shoulder arthroplasty (RSA) procedures, in the context of a prospective, randomized-controlled trial to determine the optimal treatment in patients 65 years of age and older who have glenohumeral osteoarthritis.

The Ottawa Hospital
 (4.0 away) Contact site
  • 0 views
  • 23 May, 2021
  • +4 other locations
Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?

Provoked vestibulodynia (PVD) is one major subtype of vulvar pain, affecting close to one in ten women and resulting in pain during attempts at vaginal intercourse and/or attempts to insert a digit, device or tampon into the vagina. Management involves a multidisciplinary approach, through physicians, psychologists, sex therapists and physiotherapists. …

McLean Function Measurement Lab
 (4.5 away) Contact site
  • 0 views
  • 25 Mar, 2021
  • 1 location