Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

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Found 482 clinical trials
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the APOE4/4 genotype. This is a double-blind, randomized trial with one dose of ALZ-801 compared to placebo.

Ottawa Memory Clinic
 (3.3 away) Contact site
  • 0 views
  • 28 Aug, 2021
  • +74 other locations
Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy

This is a multicenter, randomized, double-blind study to evaluate the efficacy and safety of TRM-201 (rofecoxib) versus Placebo in the treatment of patients with hemophilic arthropathy (HA) over a 12-week period (Part I) that is followed by a year-long (52 week) open-label extension (Part II) to further evaluate the safety …

Health Sciences Center
 (5.7 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +50 other locations
A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

Study CC-93538-EE-001 is a Phase 3, multicenter, multinational, randomized, double-blind, placebo-controlled induction and maintenance study to evaluate the efficacy and safety of CC- 93538 in adult and adolescent participants with eosinophilic esophagitis (EoE). The study will incorporate a 24-week Induction Phase followed by a 24-week Maintenance Phase. Participants will be …

Ottawa Allergy Research Corporation
 (5.5 away) Contact site
  • 42 views
  • 28 Aug, 2021
  • +228 other locations
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG).

generalized myasthenia gravis
weakness
The Ottawa Hospital Research Institute
 (5.8 away) Contact site
  • 3 views
  • 28 Aug, 2021
  • +139 other locations
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the APOE4/4 genotype. This is a double-blind, randomized trial with one dose of ALZ-801 compared to placebo.

Ottawa Memory Clinic
 (3.3 away) Contact site
  • 3 views
  • 05 Aug, 2021
  • +60 other locations
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will …

Novo Nordisk Investigational Site
 (5.1 away) Contact site
  • 2 views
  • 15 Sep, 2021
  • +166 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
evobrutinib
teriflunomide
Research Site 101
 (6.1 away) Contact site
  • 0 views
  • 02 Sep, 2021
  • +271 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

right heart catheterization
heart disease
macitentan 10 mg
macitentan
connective tissue disease
University of Ottawa Heart Institute
 (4.1 away) Contact site
  • 56 views
  • 09 Sep, 2021
  • +269 other locations
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy Compared With Carboplatin-Pemetrexed in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

The purpose of this study is to compare the efficacy, as demonstrated by progression-free survival (PFS), in participants treated with amivantamab in combination with chemotherapy, versus chemotherapy alone in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) characterized by EGFR Exon 20ins mutations.

lung carcinoma
pemetrexed
cancer chemotherapy
carboplatin
epidermal growth factor receptor
The Ottawa Hospital Cancer Centre
 (5.8 away) Contact site
  • 1 views
  • 26 Aug, 2021
  • +284 other locations
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR). This evaluation will provide information that brolucizumab is non-inferior to PRP with respect to the change in best corrected visual acuity at Week …

Novartis Investigative Site
 (5.8 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +93 other locations