Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

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Found 485 clinical trials
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG).

generalized myasthenia gravis
weakness
The Ottawa Hospital Research Institute
 (5.8 away) Contact site
  • 3 views
  • 22 Sep, 2021
  • +139 other locations
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the APOE4/4 genotype. This is a double-blind, randomized trial with one dose of ALZ-801 compared to placebo.

Ottawa Memory Clinic
 (3.3 away) Contact site
  • 3 views
  • 05 Aug, 2021
  • +60 other locations
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determining the superiority of lecanemab compared with placebo on the change from baseline in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) at 18 months of treatment in the Core Study. This …

Recherches Neuro-Hippocampe, Inc., d/b/a Ottawa Memory Clinic
 (3.3 away) Contact site
  • 245 views
  • 05 Jul, 2021
  • +275 other locations
DRAGON 1- Training Accreditation Implementation and Safety Evaluation of Combined PVE/HVE

Brief Summary: Some colorectal liver metastases can only be resected after inducing liver regeneration by portal vein embolization (PVE) to increase size function of the future liver remnant (FLR). While PVE is standard, embolization of portal vein and hepatic veins (PVE/HVE) on one side of the liver may faster and …

The Ottawa Hospital
 (4.0 away) Contact site
  • 0 views
  • 09 Sep, 2021
  • +36 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (2.3 away) Contact site
  • 49 views
  • 08 Sep, 2021
  • +477 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

migraine
headache
Ottawa Headache Centre Research Inc
 (2.3 away) Contact site
  • 595 views
  • 24 Jul, 2021
  • +178 other locations
A Phase 3 Multi-Center Randomized Double-Blind Placebo-Controlled Study of Fostamatinib Disodium in the Treatment of wAIHA

The primary objective of this study is to assess the efficacy of fostamatinib in subjects with warm antibody autoimmune hemolytic anemia (wAIHA).

The Ottawa Hospital
 (5.8 away) Contact site
  • 116 views
  • 31 Jul, 2021
  • +125 other locations
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries

Musculoskeletal (MSK) injuries, including limb injuries, are the most common cause for Emergency Department (ED) visits for children with pain. Broken arms and legs are known to cause moderate to severe pain in most children, yet previous research shows that children's pain in the emergency department is still under-treated. Further, …

Children's Hospital of Eastern Ontario
 (5.8 away) Contact site
  • 8 views
  • 10 May, 2021
  • +11 other locations
Long-term Safety Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have participated in a Novartis ofatumumab clinical MS study. Vaccination sub-study The purpose of this research sub-study is to find out the effects of ofatumumab on the development of antibody …

ofatumumab
tetanus
pneumococcal conjugate vaccine
Novartis Investigative Site
 (5.8 away) Contact site
  • 252 views
  • 11 Sep, 2021
  • +261 other locations
Efficacy Safety and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.

This clinical study will test the effects of a drug called apremilast in oligoarticular psoriatic arthritis with less than 5 years of disease duration. In previous studies, apremilast has been shown to be safe and efficacious in reducing signs and symptoms of psoriatic arthritis, as well as improving physical function. …

apremilast
Ottawa Hospital
 (4.0 away) Contact site
  • 279 views
  • 08 Aug, 2021
  • +268 other locations