Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 482 clinical trials
A Study to Evaluate the Efficacy and Safety of Dupilumab in Participants With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)

The primary objective of the study is to evaluate the efficacy of dupilumab on the annualized rate of exacerbations in participants with Allergic Bronchopulmonary Aspergillosis (ABPA). The secondary objectives of the study are: To evaluate the effects of dupilumab on lung function in participants with ABPA To evaluate the effects …

Regeneron Study Site
 (6.1 away) Contact site
  • 0 views
  • 17 Mar, 2021
  • +18 other locations
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the APOE4/4 genotype. This is a double-blind, randomized trial with one dose of ALZ-801 compared to placebo.

Ottawa Memory Clinic
 (3.3 away) Contact site
  • 0 views
  • 28 Aug, 2021
  • +74 other locations
Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy

This is a multicenter, randomized, double-blind study to evaluate the efficacy and safety of TRM-201 (rofecoxib) versus Placebo in the treatment of patients with hemophilic arthropathy (HA) over a 12-week period (Part I) that is followed by a year-long (52 week) open-label extension (Part II) to further evaluate the safety …

Health Sciences Center
 (5.7 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +50 other locations
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG).

weakness
generalized myasthenia gravis
The Ottawa Hospital Research Institute
 (5.8 away) Contact site
  • 3 views
  • 28 Aug, 2021
  • +139 other locations
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the APOE4/4 genotype. This is a double-blind, randomized trial with one dose of ALZ-801 compared to placebo.

Ottawa Memory Clinic
 (3.3 away) Contact site
  • 3 views
  • 05 Aug, 2021
  • +60 other locations
DRAGON 1- Training Accreditation Implementation and Safety Evaluation of Combined PVE/HVE

Brief Summary: Some colorectal liver metastases can only be resected after inducing liver regeneration by portal vein embolization (PVE) to increase size function of the future liver remnant (FLR). While PVE is standard, embolization of portal vein and hepatic veins (PVE/HVE) on one side of the liver may faster and …

The Ottawa Hospital
 (4.0 away) Contact site
  • 0 views
  • 09 Sep, 2021
  • +36 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
evobrutinib
teriflunomide
Research Site 101
 (6.1 away) Contact site
  • 0 views
  • 02 Sep, 2021
  • +271 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

macitentan
connective tissue disease
macitentan 10 mg
heart disease
hemodynamic evaluation
University of Ottawa Heart Institute
 (4.1 away) Contact site
  • 56 views
  • 09 Sep, 2021
  • +269 other locations
Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack

The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of a dual antiplatelet therapy (acetylsalicylic acid +/- clopidogrel) in patients following a recent heart attack …

troponin
ck-mb
clopidogrel
aspirin
antiplatelet therapy
University of Ottawa Heart Institute
 (4.1 away) Contact site
  • 58 views
  • 07 Sep, 2021
  • +193 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (2.3 away) Contact site
  • 37 views
  • 08 Sep, 2021
  • +477 other locations