Nepean, Canada Clinical Trials

A listing of Nepean, Canada clinical trials actively recruiting patients volunteers.

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Found 195 clinical trials
A 20-Week Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children and Adult Participants With Dravet Syndrome (ARGUS Trial) (ARGUS)

The purpose of this study is to evaluate the safety and efficacy of EPX-100 as adjunctive therapy in children and adult participants with Dravet Syndrome.

convulsive seizures
antiepileptic
tonic clonic convulsion
adjunctive therapy
tonic
Children's Hospital of Eastern Ontario
 (5.8 away) Contact site
  • 63 views
  • 17 Oct, 2022
  • +10 other locations
Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology: A Multicenter Randomized Controlled Trial

At present, it is not clear whether performing a hip arthroscopy at the same time as a PAO improves patient outcomes after surgery compared to a PAO alone. This research project will randomize patients to receive either a PAO alone, or a PAO and a hip arthroscopy at the same …

arthroscopy
osteotomy
hip arthroscopy
Ottawa Hospital Research Institute
 (5.8 away) Contact site
  • 1 views
  • 16 Oct, 2022
  • +6 other locations
A Randomized, Double-blind Controlled Trial Comparing Arthroscopic Tennis Elbow Release With Arthroscopic Debridement for the Management of Chronic Lateral Epicondylitis

We propose a randomized, double-blind controlled trial comparing arthroscopic release with arthroscopic debridement for the management of chronic tennis elbow in an effort to definitively determine whether arthroscopic tennis elbow release is an effective treatment of tennis elbow, and to further provide better recommendations for the use of this procedure, …

conservative management
The Ottawa Hospital, General Campus
 (6.1 away) Contact site
  • 76 views
  • 18 Oct, 2022
  • 1 location
REmote Cardiac MOnitoring of At-risk SYNCope Patients After Emergency Department Discharge - A Multicenter Randomized Controlled Trial: REMOSYNCED (REMOSYNCED)

Syncope (fainting) is a common reason for emergency department (ED) presentation. Fainting can be caused by heart conditions such as irregular heart rhythm (arrhythmia) that can be life-threatening, structural heart problems, or serious conditions not related to the heart. The standard or usual treatment for the majority of patients at-risk …

The Ottawa Hospital - Civic and General Campuses
 (4.0 away) Contact site
  • 0 views
  • 24 Oct, 2022
  • 1 location
A Randomized Phase III Trial of Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer [PLATON] (PLATON)

The purpose of this study is to compare the effects of ablative therapy (radiation or surgery) to all sites of disease combined with standard treatments on prostate cancer, compared to the standard or usual treatments used to treat this disease.

cfdna
metastasis
adenocarcinoma
adenocarcinoma of prostate
bone scan
Ottawa Hospital Research Institute
 (5.8 away) Contact site
  • 71 views
  • 21 Oct, 2022
  • +14 other locations
A Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

The purpose of this study is to compare the efficacy and safety of intravenous (IV) infusions of MT-3921 to placebo in subjects with acute traumatic cervical spinal cord injury. Subjects meeting eligibility criteria will enter the 6-month double-blind period. Subjects will be randomized in a 2:1 ratio to receive MT-3921 …

body mass index
cervical spinal cord injury
spinal cord
spinal cord disorder
The Ottawa Hospital
 (4.0 away) Contact site
  • 28 views
  • 21 Oct, 2022
  • +47 other locations
A Simple Exercise Program for Patients With End Stage Kidney Disease to Improve Strength and Quality of Life: A Feasibility Study

This study will be conducted over a 3 year time period. This is a trial of an exercise intervention vs. standard of care in patients receiving chronic dialysis. The specific aims will be to determine feasibility of patient recruitment, adherence to the exercise program, and efficacy of the intervention on …

drug abuse
dialysis
nephropathy
chronic renal failure
Ottawa Hospital
 (4.9 away) Contact site
  • 62 views
  • 25 Oct, 2022
  • 1 location
Cluster Randomization Trial of Peer Support for Women With Heart Disease: Women@ Heart

Women with heart disease are more likely to die or suffer another cardiac event or stroke within 5 years of an index event compared to men. They are also more likely to suffer depression and report lower quality of life. Cardiac Rehabilitation programs have been designed to address these issues, …

cabg
depression
cardiac event
angina pectoris
stable angina
University of Ottawa Heart Institute
 (5.2 away) Contact site
  • 60 views
  • 25 Oct, 2022
  • 1 location
Multi-center, Randomized, Parallel, Adaptive, Controlled Trial in Adult and Pediatric Patients With Type 1 Diabetes Using Hybrid Closed Loop System and Control (CSII, MDI and SAP) at Home

The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting. A diverse population of patients with type 1 diabetes will be studied. The study population will have a …

celiac disease
diabetes
treatment regimen
insulin
hemoglobin a1c
Children's Hospital of Eastern Ontario
 (5.8 away) Contact site
  • 82 views
  • 25 Oct, 2022
  • +14 other locations
Endoscopic Polypectomy Performed In Clinic for Chronic Rhinosinusitis With Polyps: The EPIC Randomised Controlled Trial

Chronic rhinosinusitis, also called chronic sinusitis, is a very common life-long disease affecting over 5% of the Canadian population. Its symptoms, including daily facial pain and headache, an inability to breath through the nose and complete smell loss, regularly impair one's ability to work and to enjoy and participate in …

anesthesia
other disease
COPD
headache
sinusitis
Ottawa Hospital Research Institute
 (4.0 away) Contact site
  • 1419 views
  • 15 Oct, 2022
  • +3 other locations