a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 13382 clinical trials
Featured trial
Study to evaluate HZN-825 in patients with Idiopathic Pulmonary Fibrosis (IPF)

daily (QD) or twice daily (BID)) or a placebo regimen for 52 weeks. Participants who complete the duration of this trial may be eligible to enter an open-label 52-week extension trial where all patients

diffusion capacity of the lung for carbon monoxide
pneumonia
emphysema
  • 10 views
  • 22 Sep, 2022
  • 28 locations
Featured trial
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

This study is a Phase 3 global, multicenter, placebo-controlled double-blind randomized study that will enroll participants with inoperable locally recurrent or metastatic SCAC not previously

  • 1245 views
  • 17 Sep, 2022
  • 84 locations
Featured trial
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

This study is a Phase 3 global, multicenter, placebo-controlled double-blind randomized study that will enroll participants with inoperable locally recurrent or metastatic SCAC not previously

  • 10 views
  • 07 Oct, 2022
  • 80 locations
Featured trial
Alzheimer's Disease and Precision Medicine Research Among Native People

This project intends to address the gaps in Alzheimer's disease (AD) and precision medicine (PM) research in American Indian and Alaska Native (AI/AN) populations by comparing written and video-based materials for recruitment into AD and PM research, and by creating an AD-PM registry of AI/AN individuals who are willing to …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Featured trial
Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia (PATHWAY)

The purpose of this study is to evaluate the efficacy and safety of parsclisib compared with placebo in participants with Primary Warm Autoimmune Hemolytic Anemia (wAIHA),

  • 0 views
  • 07 Oct, 2022
  • 17 locations
Featured trial
A trial evaluating TEPEZZA® in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA® administered once every 3 weeks (q3W) for 24 weeks in the treatment of participants with diffuse cutaneous systemic sclerosis (dcSSc).

  • 6 views
  • 11 Aug, 2022
  • 5 locations
Featured trial
A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

This is a nonrandomized study of ruxolitinib in combination with a standard multi-agent chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will

prednisone
mercaptopurine
dexamethasone
pegaspargase
asparaginase
  • 5 views
  • 04 Oct, 2022
  • 98 locations
Featured trial
A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). The study will focus on participants with a specific

movement disorder
depression
hoehn and yahr scale
motor symptoms
  • 0 views
  • 07 Oct, 2022
  • 2 locations
Featured trial
INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

This Phase 1/2, open-label, dose-finding study is intended to evaluate the safety and tolerability, PK, PD, and efficacy of INCB000928 administered as monotherapy or in combination with ruxolitinib in participants with MF who are transfusion-dependent or presenting with symptomatic anemia. This study will consist of 2 parts: dose escalation and …

anemia
  • 12 views
  • 07 Oct, 2022
  • 20 locations
Featured trial
A Study Evaluating Safety and Tolerability and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

<a href="https://myelofibrosisresearch.com/CW" target="_blank">www.myelofibrosisresearch.coma>


There are 4 parts to this study for which the primary objectives are to evaluate

thrombocytosis
chronic myelomonocytic leukemia
polycythemia
stem cell transplantation
polycythemia vera
  • 49 views
  • 17 Sep, 2022
  • 36 locations