Montreal, Canada Clinical Trials

A listing of Montreal, Canada clinical trials actively recruiting patients volunteers.

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Found 1014 clinical trials
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Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to assess …

McGill University Health Center Research Institute /ID# 222614
 (2.4 away) Contact site
  • 181 views
  • 29 Apr, 2021
  • +224 other locations
featured
Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

H pital Maisonneuve-Rosemont /ID# 221925
 (5.0 away) Contact site
  • 39 views
  • 29 Apr, 2021
  • +148 other locations
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A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

www.MyelofibrosisResearch.com This is a Phase 2 open-label, multicenter study evaluating tolerability and efficacy of navitoclax alone or when added to ruxolitinib in participants with myelofibrosis.

McGill University Health Center Research Institute /ID# 223976
 (2.4 away) Contact site
  • 254 views
  • 29 Apr, 2021
  • +134 other locations
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A Study to Evaluate the Safety Tolerability and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease

The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses of BIIB094 administered via intrathecal (IT) injection to participants with Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for …

dyskinesia
Montreal Neurological Institute and Hospital
 (0.9 away) Contact site
  • 251 views
  • 25 May, 2021
  • +13 other locations
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Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.

sodium oxybate
somnolence
sleep disorder
cataplexy
stimulant
CIUSS de Nord-de-I'ile-de- Montreal- Hopital de Sacre-Coeur de Montreal
 (0.2 away) Contact site
  • 23 views
  • 10 Jul, 2018
  • +52 other locations
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Niraparib Maintenance Treatment in Patients with Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Niraparib Maintenance Treatment in Patients with Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

Research Center
 (1.4 away) Contact site
  • 1940 views
  • 25 Mar, 2021
  • +106 other locations
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We are currently recruiting patients with Palmoplantar Pustulosis (PPP). This study investigates the Efficacy and safety of ANB019.

The study drug consists of a sub-cutaneous investigational treatment or a placebo, that will be administered on Day 1, followed by 3 doses of the study treatment on Days 29, Day 57 and Day 85. Several blood samples will be collected throughout the study. Your participation in the biopsy portion …

psoriasis
skin disease
skin disorder
Innovaderm Research Inc.
 (0.8 away) Contact site
  • 28 views
  • 22 Dec, 2020
  • +23 other locations
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COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 – Canada  

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements.   This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept …

epoetin alfa
Sir Mortimer B Davis Jewish General Hospital
 (3.0 away)
  • 33 views
  • 03 Aug, 2021
  • +9 other locations
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We are currently recruiting participants for the BLUEPRINT study. This study investigates the effectiveness, safety, and tolerability of the drug BLU-5937 for chronic itch in people with eczema.

The BLUEPRINT study consists of taking two tablets orally, twice a day, for a period of 4 weeks. This treatment is experimental. You will have 50% chance to receive BLU-5937 and 50% chance to receive the placebo. There will be a total of 5 visits at the clinic and 2 …

eczema
atopic dermatitis
atopic dermatitis/eczema
dermatitis
adult atopic dermatitis
Innovaderm Research
 (2.9 away) Contact site
  • 0 views
  • 10 Dec, 2020
  • +24 other locations
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INCB 18424-303: Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 1 (TRuE-AD1)

A Phase 3, randomized (2:2:1), double-blind, 8-week vehicle control efficacy and safety study of ruxolitinib followed by a randomized, double-blind, 44-week long term safety (LTS) extension period.  In the LTS period,  participants initially randomized to vehicle will receive either ruxolitinib 0.75% or 1.5% cream.  All participants will have follow-up assessments …

atopic dermatitis
eczema
atopic dermatitis/eczema
SIENA MEDICAL RESEARCH CORPORATION
 (1.4 away) Contact site
  • 246 views
  • 14 Dec, 2020
  • +37 other locations