Milton, Canada Clinical Trials

A listing of Milton, Canada clinical trials actively recruiting patients volunteers.

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Found 20 clinical trials
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Phase III, double-blind, randomised study assessing the efficacy of capivasertib + fulvestrant vs placebo + fulvestrant for the treatment of patients with locally advanced (inoperable) or metastatic HR+/HER2- breast cancer following recurrence or progression on or after AI therapy.

Research Site
 (9.2 away) Contact site
  • 50 views
  • 11 Jul, 2021
  • +223 other locations
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

Research Site
 (10.0 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +193 other locations
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for …

exercise intervention
cancer treatment
immunomodulators
x-rays
cancer
Trillium Health Partners - Credit Valley Hospital
 (9.2 away) Contact site
  • 397 views
  • 23 Jul, 2021
  • +50 other locations
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get semaglutide or placebo in addition to their diabetes medicines - which treatment the …

hypoglycemic agents
semaglutide
Novo Nordisk Investigational Site
 (7.3 away) Contact site
  • 581 views
  • 25 Jul, 2021
  • +237 other locations
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

During end-stage kidney disease, clinical guidelines suggest reducing elevated phosphate levels in the blood. However, the effect of lowering blood phosphate levels on important patient-centred outcomes has never been tested. This trial will evaluate whether compared to high levels, lowering blood phosphate levels would reduce death or major events due …

dialysis
renal failure
renal disease
blood phosphate
heart disease
Oakville Trafalgar Memorial Hospital
 (7.7 away) Contact site
  • 91 views
  • 15 Jul, 2021
  • +54 other locations
Efficacy and Safety Study of Stereotactic Body Radiotherapy (SBRT) With or Without Pembrolizumab (MK-3475) in Adults With Unresected Stage I or IIA Non-Small Cell Lung Cancer (NSCLC) (MK-3475-867/KEYNOTE-867)

The purpose of this study is to assess the efficacy and safety of stereotactic body radiotherapy (SBRT) plus pembrolizumab (MK-3475) in the treatment of adult participants with unresected stage I or IIA non-small cell lung cancer (NSCLC). The primary study hypotheses are: SBRT plus pembrolizumab prolongs Event-free Survival (EFS) compared …

lung carcinoma
mk-3475
pembrolizumab
stereotactic body radiation therapy
Trillium Health Partners - Credit Valley Hospital ( Site 0102)
 (9.2 away) Contact site
  • 121 views
  • 25 Jul, 2021
  • +178 other locations
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Phase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer (TNBC)

paclitaxel
triple-negative breast cancer
breast cancer
cancer
measurable disease
Research Site
 (9.2 away) Contact site
  • 1387 views
  • 25 Jul, 2021
  • +307 other locations
Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

The purpose of this study is to determine the efficacy and safety of multiple CSJ117 doses (0.5; 1; 2; 4 and 8 mg) inhaled once daily compared with placebo, when added to standard-of-care (SoC) asthma therapy in adult patients with uncontrolled asthma with respect to change from baseline in FEV1 …

corticosteroids
Novartis Investigative Site
 (9.1 away) Contact site
  • 47 views
  • 25 Jul, 2021
  • +135 other locations
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on cognitive decline using the Alzheimer's Disease Assessment Scale Cognitive subscale 13-item version (ADAS-Cog13).

cognitive decline
dementia
cognitive assessment
alzheimer's disease
JBN Medical Diagnostics Services, Inc.
 (9.1 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +144 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

cardiovascular disease
body mass index
overweight or obesity
Novo Nordisk Investigational Site
 (9.1 away) Contact site
  • 7712 views
  • 18 Jul, 2021
  • +1164 other locations