Longueuil, Canada Clinical Trials

A listing of Longueuil, Canada clinical trials actively recruiting patients volunteers.

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Found 1021 clinical trials
Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer Patients

This is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) NSCLC.

durvalumab
stereotactic body radiation therapy
lung carcinoma
Research Site
 (6.0 away) Contact site
  • 72 views
  • 28 Apr, 2021
  • +226 other locations
A Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumors (ARTISTRY-2)

This study will characterize the safety and tolerability and identify the recommended Phase 2 dose (RP2D) of subcutaneous (SC) ALKS 4230 as monotherapy and in combination with pembrolizumab.

Alkermes Investigational Sites
 (2.8 away) Contact site
  • 5 views
  • 03 Jun, 2021
  • +32 other locations
Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

The purpose of this study is to continue to assess safety and tolerability, and to allow continued access to study treatment for subjects already receiving spartalizumab as single agent or in combination with other study treatments.

Novartis Investigative Site
 (6.3 away) Contact site
  • 0 views
  • 05 Aug, 2021
  • +34 other locations
Study of Talimogene Laherparepvec In Children With Advanced Non CNS Tumors

This is a phase 1 study to evaluate the safety of intralesional talimogene laherparepvec administration in pediatric subjects with advanced non-CNS tumors that are amenable to direct injection

Research Site
 (6.0 away) Contact site
  • 0 views
  • 27 Aug, 2021
  • +45 other locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

This is an open-label, randomized, multi-center, comparator Phase II trial looking at the addition of Bevacizumab to Vinblastine in chemotherapy nave pediatric patients with progressive Low Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm …

auditory test
corticosteroids
platelet count
BRAF
neutrophil count
Centre Hospitalier Universitaire Sainte-Justine
 (3.6 away) Contact site
  • 0 views
  • 24 Jan, 2021
  • +23 other locations
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, safety and pharmacokinetics (PK) of macitentan in children.

heart disease
connective tissue disease
hypertension
macitentan
Sainte Justine Hospital
 (6.0 away) Contact site
  • 176 views
  • 14 Aug, 2021
  • +106 other locations
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

Dr. Annie-Claire Nadeau-Fredette
 (3.5 away) Contact site
  • 57 views
  • 26 Jan, 2021
  • +97 other locations
Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)

This study will assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of escalating doses of quavonlimab when used in combination with pembrolizumab in participants with advanced solid tumors.

Centre Hospitalier de l Universite de Montreal - CHUM ( Site 1102)
 (2.8 away) Contact site
  • 774 views
  • 19 Sep, 2021
  • +55 other locations
International Subarachnoid Aneurysm Trial II

The purpose of this study is to compare the clinical outcome of surgical clipping and endovascular coiling for ruptured intracranial aneurysms not included in the original ISAT Study.

Centre Hospitalier de l'Universit de Montr al - H pital Notre Dame
 (2.7 away) Contact site
  • 24 views
  • 04 Aug, 2021
  • +5 other locations
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

acalabrutinib
cyclin d1
rituximab
bendamustine
Research Site
 (3.0 away) Contact site
  • 1279 views
  • 17 Sep, 2021
  • +252 other locations